Recombinant Human Glucagon receptor (GCGR), partial
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Catalog number
MBS966020
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Price
Please ask
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Size
0.5 mg (Baculovirus)
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Products_type
Recombinant Protein
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Products_short_name
[Glucagon receptor (GCGR)]
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Other_names
[glucagon receptor; Glucagon receptor; glucagon receptor; glucagon receptor]
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Products_gene_name
[GCGR]
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Other_gene_names
[GCGR; GCGR; GGR; GL-R; GL-R]
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Purity
>85% (SDS-PAGE)
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Form
Lyophilized or liquid (Format to be determined during the manufacturing process)
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Storage_stability
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
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Description
Glucagon gene and the glucagon like peptide or GLP1 gene are peptide hormones, produced by alpha cells of the pancreas to raise the concentration of glucose in the blood as opposite of insulin, which lowers the glucose. Anti human glucagon and glp1 antibodies are used to study diabetes. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
GCGR
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Short name
Recombinant Glucagon receptor (GCGR), partial
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
E Coli or Yeast or Baculovirus or Mammalian Cell
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Species
Human, Humans
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Alternative name
Rec. H. sapiens Glucagon receptor (gluca this GO n receptor), partial
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Alternative technique
rec
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Alternative to gene target
gluca this GO n receptor, GGR and GL-R, GCGR and IDBG-227533 and ENSG00000215644 and 2642, peptide hormone binding, Plasma membranes, Gcgr and IDBG-214830 and ENSMUSG00000025127 and 14527, BT.27844 and IDBG-642400 and ENSBTAG00000003786 and 515433
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Gene info
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Identity
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Gene
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Long gene name
glucagon receptor
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Synonyms
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GenBank acession
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Locus
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Discovery year
1994-03-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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