anti-LIN28 Antibody

• Catalog number
  25-209
• Price
  Please ask
• Size
  50 ug

• Gene info
  LIN28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. The association of LIN28 with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. IT binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. LIN28 is Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression.
• Gene names
  LIN28, CSDD1, FLJ12457, LIN-28, LIN28A, ZCCHC1, LIN28, lin-28A
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LIN28.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  LIN28 antibody can be used for detection of LIN28 by ELISA at 1:62500. LIN28 antibody can be used for detection of LIN28 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store LIN28 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human
• Omim nr
  13375938
• Ncbi nr
  NP_078950
• KDa
  23 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  79727
• GENE symbol
  LIN28A
• Antigene name
  lin-28 homolog A (C. elegans)
• Source
  Homo sapiens
• Protein nr
  Q9H9Z2
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  LIN28  
• Gene symbol
  LIN28A
• Short name
  anti-LIN28 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toLIN28 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:15986
• Gene
  LIN28A
• Long gene name
  lin-28 homolog A
• Synonyms gene
  • LIN28
• Synonyms gene name
  • lin-28 homolog (C. elegans)
• Synonyms
  • LIN-28
  • FLJ12457
  • ZCCHC1
  • CSDD1
• GenBank acession
  • AF521099
• Locus
  1p36.11
• Discovery year
  2003-07-21
• Entrez gene record
  79727
• Pubmed identfication
  • 12798299
• RefSeq identity
  • NM_024674
• Classification
  • Zinc fingers CCHC-type
• VEGA ID
  OTTHUMG00000003550

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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