COX-2 Inhibitor V, FK3311

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Cas number

116686-15-8
Chemical s molecular weight

341.33
Chemical s main applications

COX-2 Inhibitor V, FK3311 is a selective Cox-2 inhibitor and NSAID.
Chemical s formula

C15H13F2NO4S
Physical properties

No Data Available
Melting temperature

No Data Available
Boiling temperature

No Data Available
Chemical s soluble in

No Data Available
Stability conditions

No Data Available
Storage

No Data Available
Chemical s specifications
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Gene target

COX-2 Inhibitor FK3311
Gene symbol

PTGS2, COX8A, MT-CO2, MIR1289-2, MIR521-2, MIR509-2, MIR512-2, MIR7-2, MIR329-2, RNU6-2
Short name

COX-2 Inhibitor V, FK3311
Alternative name

COX-2 suppressor V, FK3311

Identity

HGNC:9605
Gene

PTGS2
Long gene name

prostaglandin-endoperoxide synthase 2
Synonyms gene name
- prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Synonyms
- COX2
Synonyms name
- prostaglandin G/H synthase 2
- cyclooxygenase 2
GenBank acession
- D28235
Locus

1q31.1
Discovery year

1992-10-28
Entrez gene record

5743
Pubmed identfication
- 1380156
RefSeq identity
- NM_000963
VEGA ID

OTTHUMG00000035473

Identity

HGNC:2294
Gene

COX8A
Long gene name

cytochrome c oxidase subunit 8A
Synonyms gene
- COX8
Synonyms gene name
- cytochrome c oxidase subunit VIII
- cytochrome c oxidase subunit VIIIA (ubiquitous)
Synonyms
- COX8-2
- COX8L
- VIII-L
- COX
- VIII
GenBank acession
- J04823
Locus

11q13.1
Discovery year

1989-06-30
Entrez gene record

1351
Pubmed identfication
- 2543673
- 2847943
- 26685157
RefSeq identity
- NM_004074
Classification
- Mitochondrial complex IV: cytochrome c oxidase subunits
VEGA ID

OTTHUMG00000167785

Identity

HGNC:7421
Gene

MT-CO2
Long gene name

mitochondrially encoded cytochrome c oxidase II
Synonyms gene
- MTCO2
Synonyms gene name
- cytochrome c oxidase II
Synonyms
- COX2
- CO2
Locus

mitochondria
Discovery year

1989-10-12
Entrez gene record

4513
Pubmed identfication
- 1712754
- 1989603
RefSeq identity
- YP_003024029
Classification
- Mitochondrial complex IV: cytochrome c oxidase subunits
- Mitochondrially encoded protein coding genes