Human CellExp™ Siglec-6 / CD327 Protein, Fc Tag
-
Catalog number
7882-10
-
Price
Please ask
-
Size
10 ug
-
-
Synonyms
SIGLEC6, CD327, CD33L, CD33L1, OBBP1, OB-BP1, CDw327
-
Alternative_names
SIGLEC6, CD327, CD33L, CD33L1, OBBP1, OB-BP1, CDw327
-
Description
A cell surface protein primarily on the surface of immune cells that mediates sialic-acid dependent binding to cells.
-
Recombinant
Yes
-
Source
HEK293 cells
-
Purity by SDS PAGE
>92%
-
Assay
SDS-PAGE
-
Biological activity
Measured by its ability to bind biotinylated Neu5Ac alpha 2-6GalNAc alpha (sialyl-Tn).
-
Molecular Weight
60.3 kDa
-
Storage Temp
+4°C
-
Shipping
Gel Pack
-
Shelf Life
12 months
-
Appearance
Dry powder
-
Physical form description
Lyophilized powder
-
Reconstitution Instructions
. Reconstitute in sterile deionized water to a stock solution of 200 µg/mL. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% (W/V) HSA or BSA) is recommended for further dilution and long term storage.
-
Background Information
Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1). SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
-
Amino acid sequence
Gln 16 - Val 320
-
Handling
Centrifuge the vial prior to opening.
-
Usage
For Research Use Only! Not to be used in humans
-
-
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Gene target
-
Gene symbol
SIGLEC6
-
Short name
CellExp™ Siglec-6 / CD327 Protein, Fc Tag
-
Technique
FC, Tags
-
Label
Fc Tag
-
Species
Humans
-
Alternative name
H. sapiens CellExp™ Siglec-6 / CD327 Protein, fragment c detection labelled
-
Gene info
Product images
Similar products
