anti-AGER Antibody

• Catalog number
  29-611
• Price
  Please ask
• Size
  100 ug

• Gene info
  AGER mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. It is receptor for amyloid beta peptide.This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms.
• Gene names
  AGER, MGC22357, RAGE
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by protein A chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AGER.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  AGER antibody can be used for detection of AGER by ELISA at 1:62500. AGER antibody can be used for detection of AGER by western blot at 2.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store AGER antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human
• Omim nr
  26787962
• Ncbi nr
  NP_751947
• KDa
  38 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  177
• GENE symbol
  AGER
• Antigene name
  advanced glycosylation end product-specific receptor
• Source
  Homo sapiens
• Protein nr
  A2BFI7
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  AGER  
• Gene symbol
  AGER
• Short name
  anti-AGER Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toAGER (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  advanced glycosylation end product-specific receptor, RAGE, AGER and IDBG-80463 and ENSG00000204305 and 177, S100 protein binding, Extracellular, Ager and IDBG-172144 and ENSMUSG00000015452 and 11596, AGER and IDBG-633065 and ENSBTAG00000014420 and 280986

Gene info

• Identity
  HGNC:320
• Gene
  AGER
• Long gene name
  advanced glycosylation end-product specific receptor
• Synonyms
  • RAGE
  • SCARJ1
  • sRAGE
• Synonyms name
  • receptor for advanced glycation end-products
• GenBank acession
  • M91211
• Locus
  6p21.32
• Discovery year
  1994-10-17
• Entrez gene record
  177
• Pubmed identfication
  • 7713518
• RefSeq identity
  • NM_001136
• Classification
  • Scavenger receptors
  • C2-set domain containing
• VEGA ID
  OTTHUMG00000031120

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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