EAF2 (ELL-associated Factor 2, Testosterone-regulated Apoptosis Inducer and Tumor Suppressor Protein, TRAITS, BM-040, U19)

• Catalog number
  MBS6008681
• Price
  Please ask
• Size
  0,05 mg

• Other size
  please contact us to order other different size
• Description
  This 1 is suited for programmed cell-death studies. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.

• Gene target
  EAF2   ELL-associated   Factor   Testosterone-regulated   Inducer   Tumor   Suppressor   Protein   TRAITS   BM-040   U19  
• Gene symbol
  EAF2, ELL, SNORA74A, SNORA74B, PHF21A, SPARC, ZNF644, EIF4A2, EXOC1, RSRC1
• Short name
  EAF2 (ELL-associated Factor 2, Testosterone-regulated Apoptosis Inducer Tumor Suppressor Protein, TRAITS, BM-040, U19)
• Technique
  apoptosis, apoptosis pathway
• Alternative name
  ELL associated factor 2 (ELL-associated Factor 2, Testosterone-regulated programmed cellular destruction Inducer and Tumor Suppressor Protein, TRAITS, BM-040, U19)
• Alternative technique
  celldeath
• Alternative to gene target
  ELL associated factor 2, EAF2 and IDBG-52225 and ENSG00000145088 and 55840, protein binding, nuclei, Eaf2 and IDBG-158420 and ENSMUSG00000022838 and 106389, EAF2 and IDBG-633095 and ENSBTAG00000013070 and 613523
• Tissue
  tumor

Gene info

• Identity
  HGNC:23115
• Gene
  EAF2
• Long gene name
  ELL associated factor 2
• Synonyms
  • BM040
  • TRAITS
  • U19
• GenBank acession
  • AF517829
• Locus
  3q13.33
• Discovery year
  2003-09-17
• Entrez gene record
  55840
• Pubmed identfication
  • 12446457
  • 12907652
• RefSeq identity
  • NM_018456
• VEGA ID
  OTTHUMG00000159424

Gene info

• Identity
  HGNC:23114
• Gene
  ELL
• Long gene name
  elongation factor for RNA polymerase II
• Synonyms gene
  • C19orf17
• Synonyms gene name
  • chromosome 19 open reading frame 17
  • elongation factor RNA polymerase II
• Synonyms
  • Men
  • ELL1
  • PPP1R68
• Synonyms name
  • protein phosphatase 1, regulatory subunit 68
  • eleven-nineteen lysine-rich leukemia gene
• GenBank acession
  • U16282
• Locus
  19p13.11
• Discovery year
  2003-09-17
• Entrez gene record
  8178
• Pubmed identfication
  • 7991593
  • 8596958
• RefSeq identity
  • NM_006532
• Classification
  • Super elongation complex
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000183364

Gene info

• Identity
  HGNC:10119
• Gene
  SNORA74A
• Long gene name
  small nucleolar RNA, H/ACA box 74A
• Synonyms gene
  • RNU19
• Synonyms gene name
  • RNA, U19 small nucleolar
• Synonyms
  • U19
• GenBank acession
  • X94290
• Locus
  5q31.2
• Discovery year
  1999-12-14
• Entrez gene record
  26821
• Pubmed identfication
  • 8657112
  • 9630250
• RefSeq identity
  • NR_002915
• Classification
  • Small nucleolar RNAs, H/ACA box

Gene info

• Identity
  HGNC:32660
• Gene
  SNORA74B
• Long gene name
  small nucleolar RNA, H/ACA box 74B
• Synonyms
  • U19-2
• GenBank acession
  • AM055743
• Locus
  5q35.1
• Discovery year
  2016-01-13
• Entrez gene record
  677841
• Pubmed identfication
  • 15199136
  • 16381836
  • 16361266
• RefSeq identity
  • NR_002988
• Classification
  • Small nucleolar RNAs, H/ACA box

Gene info

• Identity
  HGNC:24156
• Gene
  PHF21A
• Long gene name
  PHD finger protein 21A
• Synonyms
  • BHC80
  • KIAA1696
  • BM-006
• GenBank acession
  • AL359593
• Locus
  11p11.2
• Discovery year
  2005-02-07
• Entrez gene record
  51317
• Pubmed identfication
  • 11214970
  • 12032298
• RefSeq identity
  • NM_016621
• Classification
  • PHD finger proteins
• VEGA ID
  OTTHUMG00000167038

Gene info

• Identity
  HGNC:11219
• Gene
  SPARC
• Long gene name
  secreted protein acidic and cysteine rich
• Synonyms gene
  • ON
• Synonyms gene name
  • osteonectin
• Synonyms
  • ONT
  • BM-40
• Synonyms name
  • cysteine-rich protein
  • secreted protein acidic and rich in cysteine
• Locus
  5q33.1
• Discovery year
  2001-06-22
• Entrez gene record
  6678
• Pubmed identfication
  • 2838412
  • 3410046
• RefSeq identity
  • NM_003118
• Classification
  • SPARC family
• VEGA ID
  OTTHUMG00000130122

Gene info

• Identity
  HGNC:29222
• Gene
  ZNF644
• Long gene name
  zinc finger protein 644
• Synonyms
  • KIAA1221
  • BM-005
  • MGC60165
  • MGC70410
• GenBank acession
  • AB033047
• Locus
  1p22.2
• Discovery year
  2004-11-08
• Entrez gene record
  84146
• Pubmed identfication
  • 10574462
• RefSeq identity
  • NM_032186
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000010078

Gene info

• Identity
  HGNC:3284
• Gene
  EIF4A2
• Long gene name
  eukaryotic translation initiation factor 4A2
• Synonyms gene
  • EIF4F
• Synonyms gene name
  • eukaryotic translation initiation factor 4A, isoform 2
• Synonyms
  • DDX2B
  • EIF4A
  • BM-010
• GenBank acession
  • D30655
• Locus
  3q27.3
• Discovery year
  1995-05-10
• Entrez gene record
  1974
• Pubmed identfication
  • 8521730
• RefSeq identity
  • NM_001967
• Classification
  • DEAD-box helicases
  • Small nucleolar RNA protein coding host genes
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000156564

Gene info

• Identity
  HGNC:30380
• Gene
  EXOC1
• Long gene name
  exocyst complex component 1
• Synonyms gene
  • SEC3L1
• Synonyms gene name
  • SEC3-like 1 (S. cerevisiae)
• Synonyms
  • SEC3
  • FLJ10893
  • BM-102
  • Sec3p
• GenBank acession
  • AK027047
• Locus
  4q12
• Discovery year
  2004-01-08
• Entrez gene record
  55763
• Pubmed identfication
  • 11042152
  • 11406615
• RefSeq identity
  • NM_018261
• Classification
  • Exocyst complex
• VEGA ID
  OTTHUMG00000102165

Gene info

• Identity
  HGNC:24152
• Gene
  RSRC1
• Long gene name
  arginine and serine rich coiled-coil 1
• Synonyms gene name
  • arginine/serine-rich coiled-coil 1
• Synonyms
  • MGC12197
  • BM-011
  • SRrp53
  • SFRS21
• Synonyms name
  • splicing factor, arginine/serine-rich 21
• GenBank acession
  • AF208853
• Locus
  3q25.32
• Discovery year
  2005-02-25
• Entrez gene record
  51319
• Pubmed identfication
  • 15798186
  • 19065146
• RefSeq identity
  • NM_016625
• VEGA ID
  OTTHUMG00000158758

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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