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Azidothymidine

Azidothymidine is available 4 times from Biovision labs

B1113-10 | Azidothymidine size: 2X10 mg | 317.91 USD

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B1113-50 | Azidothymidine size: 50 mg | 425.78 USD

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B1113-50 | Azidothymidine for cell activation size: 50 mg | 334.94 USD

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B1113-10 | Azidothymidine for cell activation size: 10 mg | 137.38 USD

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Alternate Name/Synonyms 3'-Azido-3'-deoxythymidine; AZT; Zidovudine
Appearance White solid
Formulation N/A
CAS Number 30516-87-1
Peptide sequence N/A
Molecular Formula C₁₀H₁₃N₅O₄
Molecular Weight 267.24
Purity ≥98% by HPLC
Solubility/Reconstitution Instructions DMSO (>25 mg/ml) or H2O (>10 mg/ml)
Handling Protect from air and moisture
Tagline A nucleoside reverse transcriptase inhibitor and homology directed repair (HDR) blocker
Storage Temp. -20°C
Shipping Conditions gel pack
Shelf Life 36 months
MDL Number MFCD00006536
PubChem CID 35370
Category Biochemicals
Description Azidothymidine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC₅₀ = 3 nM) with low cytotoxicity (CC₅₀ > 5 μM). Displays 100-fold selectivity for HIV reverse transcriptase over DNA polymerase α. Suppresses HIV-1 replication and enhances cell viability in HIV-1 infected T cells. Antiretroviral agent. Also decreases CRISPR-mediated homology directed repair (HDR) efficiency.
CAS number 30516-87-1
Molecular weight 267.24
Other name 3'-Azido-3'-deoxythymidine; AZT; Zidovudine
Molecular formula C₁₀H₁₃N₅O₄
Physical appearance White solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥98% by HPLC
Reconstitute instructions DMSO (>25 mg/ml) or H2O (>10 mg/ml)
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 36 months
Storage instructions Protect from air and moisture
Alternative technique blots
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