FTY720, Sphingosine-1-phosphate S1P receptor agonist
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Catalog numberSIH-536-25MG
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PricePlease ask
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Size25 mg
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Stock availabilitIn StockIn Stock
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CAS number162359-56-0
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DescriptionSphingosine-1-phosphate S1P receptor agonist
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Molecular weight343,9 g/mol
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Primary research fieldsCell signaling, Neuroscience, Immunology
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Other name2-Amino-2-[2-(4-octyl-phenyl)-ethyl]-propane-1,3-diol hydrochloride, Fingolimod hydrochloride, FTY-720, FTY720, FTY 720, Fingolimod, Fingolimod HCl
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Product categorySmall Molecules
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Product typeAgonist
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Chemical formulaC19H33NO2
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OriginSynthetic
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Purity pourcentage>98% (TLC); NMR (Conforms)
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Soluble inSoluble in DMSO (100 mg/ml) or ethanol (40 mg/ml)
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Physical appearanceWhite solid
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Storage recommendations-20ºC
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Shipping recommendationsShipped Ambient
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Safety informationClassification: D2B Toxic Material Causing Other Toxic Effects - Moderate skin irritant, Moderate eye irritant Hazard statement(s): H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H412 Harmful to aquatic life with long lasting effects. Precautionary statement(s): P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P273 Avoid release to the environment. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
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PubChem number107969
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Scientific contextSee included datasheet or contact our support service
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BibliographyRefer to NCBI PubMed
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Release date30/Aug/2016
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PubMed numberRefer to PubMed
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Tested applicationsTo be tested
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Tested reactivityTo be tested
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Representative figure legendChemical structure of FTY720 (SIH-536), a Sphingosine-1-phosphate S1P receptor agonist. CAS #: 162359-56-0. Molecular Formula: C19H33NO2. Molecular Weight: 343.9 g/mol. Chemical structure of FTY720, a Sphingosine-1-phosphate S1P receptor agonist (SIH-536). CAS # 162359-56-0. Molecular Formula: C19H33NO2.
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Warning informationNon-hazardous
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Country of productionCanada
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Total weight kg0.25
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Net weight g0.025
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Additional descriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolMBTPS1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1, MIR16-1
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Short nameFTY720, Sphingosine-1-phosphate S1P receptor agonist
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Alternative nameFTY720, Sphingosine-1-phosphate S1P receptor agonist
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Gene info
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Identity
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Gene
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Long gene namemembrane bound transcription factor peptidase, site 1
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Synonyms gene name
- membrane-bound transcription factor protease, site 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-03-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Proprotein convertase subtilisin/kexin family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 101-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR101 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 16-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR15/16 family