OTX1 + OTX2 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-11958R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  OTX1 + OTX2 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-OTX1 + OTX2 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  OTX1 + OTX2
• Specificity
  This is a highly specific antibody against OTX1 + OTX2.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  30-80/354
• Subcellular location
  Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OTX1 + OTX2
• Gene ID Number
  5015, 5013
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Transcription factors, OTX1 and OTX2, are two murine homologs of the Drosophila orthodenticle (OTD), show a limited amino acid sequence divergence. OTX1 and OTX2 play an important role during early and later events required for proper brain development in that they are involved in the processes of induction, specification and regionalization of the brain. OTX1 is involved in corticogenesis, sensory organ development and pituitary functions, while OTX2 is necessary earlier in development, for the correct anterior neural plate specification and organization of the primitive streak. OTX2 is also required in the early specification of the neuroectoderm, which is destined to become the fore-midbrain, and both OTX1 and OTX2 co-operate in patterning the developing brain through a dosage-dependent mechanism. A molecular mechanism depending on a precise threshold of OTX proteins is necessary for the correct positioning of the isthmic region and for anterior brain patterning. The genes which encode OTX1 and OTX2 map to human chromosomes 2p13 and 14q21-q22, respectively.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  FLJ38361; Homeobox protein OTX 1; Homeobox protein OTX1; Homeobox protein OTX2; MCOPS 5; MCOPS5; MGC15736; MGC45000; Orthodenticle 1; Orthodenticle 2; Orthodenticle homeobox 1; Orthodenticle homeobox 2; Orthodenticle homolog 1; Orthodenticle homolog 2 Drosophila; Orthodenticle homolog 2; Orthodenticle1; Orthodenticle2; Otx 1; Otx 2; otx1; OTX1_HUMAN; otx2; OTX2_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-OTX1 + OTX2 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  OTX1   OTX2  
• Gene symbol
  OTX1, OTX2, OTX2-AS1
• Short name
  Anti-OTX1 + OTX2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  OTX1 + OTX2 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8521
• Gene
  OTX1
• Long gene name
  orthodenticle homeobox 1
• Synonyms gene name
  • orthodenticle (Drosophila) homolog 1
  • orthodenticle homolog 1 (Drosophila)
• Locus
  2p15
• Discovery year
  1994-02-08
• Entrez gene record
  5013
• Pubmed identfication
  • 7959790
• Classification
  • PRD class homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000129454

Gene info

• Identity
  HGNC:8522
• Gene
  OTX2
• Long gene name
  orthodenticle homeobox 2
• Synonyms gene name
  • orthodenticle homolog 2 (Drosophila)
• GenBank acession
  • AF298117
• Locus
  14q22.3
• Discovery year
  1994-02-08
• Entrez gene record
  5015
• Pubmed identfication
  • 7959790
• RefSeq identity
  • NM_021728.
• Classification
  • PRD class homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000152338
• Locus Specific Databases
  • LOVD
  • LRG_718

Gene info

• Identity
  HGNC:43906
• Gene
  OTX2-AS1
• Long gene name
  OTX2 antisense RNA 1 (head to head)
• Synonyms gene name
  • OTX2 antisense RNA 1 (non-protein coding)
  • OTX2 antisense RNA 1
• Synonyms
  • OTX2OS1
• GenBank acession
  • BC041486
• Locus
  14q22.3
• Discovery year
  2012-05-01
• Entrez gene record
  100309464
• Pubmed identfication
  • 15703187
• RefSeq identity
  • NR_029385
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000171304

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products