CD74 Antibody

• Catalog number
  GEN438491
• Price
  Please ask
• Size
  100ug

• Also known as
  CD74
• Other names
  N/A; N/A; HLA class II histocompatibility antigen gamma chain; p33; HLA-DR-gamma; MHC HLA-DR gamma chain; Ia-associated invariant chain; gamma chain of class II antigens; HLA-DR antigens-associated invariant chain; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule, major histocompatibility complex, class II invariant chain; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  CD74
• Gene name synonims
  N/A
• Other gene names
  CD74; N/A; II; DHLAG; HLADG; Ia-GAMMA; N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1, kappa
• Clone
  LN-2
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD74  
• Gene symbol
  CD74
• Short name
  CD74 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Anti-CD74
• Alternative technique
  antibodies
• Alternative to gene target
  CD74 molecule, major histocompatibility complex, class II invariant chain, DHLAG and HLADG and Ia-GAMMA and II, CD74 and IDBG-53594 and ENSG00000019582 and 972, MHC class II protein binding, Cell surfaces, Cd74 and IDBG-150302 and ENSMUSG00000024610 and 16149, BT.46809 and IDBG-646288 and ENSBTAG00000015228 and 613384

Gene info

• Identity
  HGNC:1697
• Gene
  CD74
• Long gene name
  CD74 molecule
• Synonyms gene
  • DHLAG
• Synonyms gene name
  • CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  • CD74 molecule, major histocompatibility complex, class II invariant chain
• Synonyms
  • CLIP
• Synonyms name
  • HLA-DR-gamma
  • Ia-associated invariant chain
  • gamma chain of class II antigens
  • MHC HLA-DR gamma chain
  • class II MHC-associated invariant chain peptide
• Locus
  5q33.1
• Discovery year
  1986-01-01
• Entrez gene record
  972
• Pubmed identfication
  • 6324166
  • 3001652
• RefSeq identity
  • NM_004355
• Classification
  • CD molecules
• VEGA ID
  OTTHUMG00000163559

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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