LRIG1, Lig-1 (40 µg, ALP-conjugated)

• Catalog number
  AS06 148-ALP
• Price
  Please ask
• Size
  40 µg

• Available ordering format
  Liquid in PBS pH 7.4, conjugated to ALP
• Immunogen
  KLH-conjugated synthetic peptide; the peptide corresponds to part of the cytoplasmic tail (C-terminal part) of the protein, not the ectodomain
• Raised in
  Rabbit
• Clonality
  Polyclonal
• Clone
  Polyclonal
• Purification
  Affinity purified IgG
• How to reconstitute
  See included datasheet or contact our support service
• Storage condition
  Store at +4°C for 12-18 months. A preservative may be added for long time storage up to 2 years.
• Verified applications
  Western blot (WB), immunolocalization (IL)
• Connected products
  AS06 156 | anti-LRIG1 hen antibodySecondary antibodies
• Recommended dilutions for use
  1 µg/ml (WB), 1: 100 (IL)
• Molecular weight expected аpparent
  143 kDa
• Verified reactivity
  human, mice
• Possible reactivity
  human
• No reactivity
  no confirmed exceptions from predicted reactivity known in the moment
• Supplementary information
  immunoblotting demonstrated LRIG1 protein in tissue lysates from normal human prostate, mammary epithelial cells, ileum, stomach, lung, and cerebral cortex
• References
  Refer to PubMed
• Scientific context
  LRIG1 protein Q96JA1 is coded by a gene on a chromosome band 3p14.3, this region is known to be deleted in various human cancers. LRIG1 is considered to be a a tumour suppressor gene in humans. LRIG1 is an integral cell-surface membrane protein that is expressed by specific cells in various human tissues and that its 143-kDa form might be cleaved into 111-kDa and 32-kDa fragments. The LRIG1 protein may inhibit the growth of tumors of glial cells and the down-regulation of the LRIG1 gene may be involved in the development and progression of the tumor.
• Notes
  Peptide used to elicit Lrig1 antibody is not conserved in Lrig3 protein.
• Protein number
  Q96JA1
• TAIR number
  Refer to NCBI
• Hyperlink

• Gene target
  LRIG1   Lig-1   ALP-conjugated  
• Gene symbol
  PDLIM3, ASRGL1, ATRNL1, SLPI, CCL27, LRIG1
• Short name
  LRIG1, Lig-1 (40 µg, ALP-conjugated)
• Technique
  antibody Conjugates
• Alternative name
  leucine-rich repeats and immunoglobulin-like domains 1, Lig-1 (40 µg, ALP-coupled)
• Alternative to gene target
  leucine-rich repeats and immunoglobulin-like domains 1, LIG-1 and LIG1, LRIG1 and IDBG-43579 and ENSG00000144749 and 26018, protein binding, Plasma membranes, Lrig1 and IDBG-171701 and ENSMUSG00000030029 and 16206, LRIG1 and IDBG-645083 and ENSBTAG00000010360 and 505750

Gene info

• Identity
  HGNC:20767
• Gene
  PDLIM3
• Long gene name
  PDZ and LIM domain 3
• Synonyms
  • ALP
• GenBank acession
  • AF002280
• Locus
  4q35.1
• Discovery year
  2004-02-06
• Entrez gene record
  27295
• Pubmed identfication
  • 10063829
  • 8828038
• RefSeq identity
  • NM_014476
• Classification
  • PDZ domain containing
  • LIM domain containing
• VEGA ID
  OTTHUMG00000160412
• Locus Specific Databases
  • LRG_752

Gene info

• Identity
  HGNC:16448
• Gene
  ASRGL1
• Long gene name
  asparaginase and isoaspartyl peptidase 1
• Synonyms gene name
  • asparaginase like 1
• Synonyms
  • FLJ22316
  • ALP1
  • ALP
• Synonyms name
  • asparaginase-like 1 protein
• Locus
  11q12.3
• Discovery year
  2001-08-29
• Entrez gene record
  80150
• Pubmed identfication
  • 11984834
  • 28671681
  • 27106100
• RefSeq identity
  • NM_001083926
• VEGA ID
  OTTHUMG00000167513

Gene info

• Identity
  HGNC:29063
• Gene
  ATRNL1
• Long gene name
  attractin like 1
• Synonyms gene name
  • attractin-like 1
• Synonyms
  • KIAA0534
  • FLJ45344
  • ALP
• GenBank acession
  • AB011106
• Locus
  10q25.3
• Discovery year
  2004-03-04
• Entrez gene record
  26033
• Pubmed identfication
  • 9628581
• RefSeq identity
  • NM_207303
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000019096

Gene info

• Identity
  HGNC:11092
• Gene
  SLPI
• Long gene name
  secretory leukocyte peptidase inhibitor
• Synonyms gene name
  • secretory leukocyte protease inhibitor (antileukoproteinase)
• Synonyms
  • HUSI-I
  • ALK1
  • ALP
  • BLPI
  • HUSI
  • WAP4
  • WFDC4
• Synonyms name
  • antileukoproteinase
• GenBank acession
  • X04502
• Locus
  20q13.12
• Discovery year
  1998-04-24
• Entrez gene record
  6590
• Pubmed identfication
  • 3640338
  • 12206714
• Classification
  • WAP four-disulfide core domain containing
• VEGA ID
  OTTHUMG00000033075

Gene info

• Identity
  HGNC:10626
• Gene
  CCL27
• Long gene name
  C-C motif chemokine ligand 27
• Synonyms gene
  • SCYA27
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 27
  • chemokine (C-C motif) ligand 27
• Synonyms
  • ALP
  • ILC
  • CTACK
  • skinkine
  • ESkine
  • PESKY
  • CTAK
• Synonyms name
  • CC chemokine ILC
  • IL-11 Ralpha-locus chemokine
  • cutaneous T-cell attracting chemokine
• GenBank acession
  • AJ243542
• Locus
  9p13.3
• Discovery year
  1999-07-30
• Entrez gene record
  10850
• Pubmed identfication
  • 10556532
  • 10588729
• RefSeq identity
  • NM_006664
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000019834

Gene info

• Identity
  HGNC:17360
• Gene
  LRIG1
• Long gene name
  leucine rich repeats and immunoglobulin like domains 1
• Synonyms
  • LIG-1
  • DKFZP586O1624
  • LIG1
• Synonyms name
  • ortholog of mouse integral membrane glycoprotein LIG-1
  • leucine-rich repeat protein LRIG1
• GenBank acession
  • AB050468
• Locus
  3p14.1
• Discovery year
  2002-08-23
• Entrez gene record
  26018
• Pubmed identfication
  • 11414704
  • 12234026
• RefSeq identity
  • NM_015541
• Classification
  • I-set domain containing
• VEGA ID
  OTTHUMG00000158727

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