This antibody has been succesfully tested for use in following methods: Western blot, Immunoprecipitation
Target of this antibody: TPX2
Formulation of this antibody: 100 µl purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Alternative names of antibody target: TPX2, TPX-2, Microtubule-associated protein TPX2 homolog, DIL2, DIL-2, Differentially expressed in lung cells, HCA519, Hepatocellular carcinoma-associated antigen 519, REPP86, Restricted expression proliferatio
Recommended usage: Western blotting (1:500 – 1:2000) and Immunoprecipitation. However, the optimal concentrations should be determined individually. The antibody recognizes the human TPX2. Reactivity to other species has not been tested.
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
Antibody host: Rabbit
This antibody reacts with: Human
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
Purification method: Affinity purified
Immunogene sequence: Synthetic peptide from human TPX2
How to handle this antibody: The antibody solution should be gently mixed before use.
Background information: TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2. TPX2 is inactivated by binding to importin a, a nuclear import factor. Finally, the suppression of TPX2 with RNA interference causes defects in microtubule organization during mitosis.
Form of antibody: Liquid
Concentration of antibody: N/A
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Short name anti-TPX2 Antibody
Technique Antibody, anti
Alternative name antibody to-TPX2, microtubule-associated, homolog (Xenopus laevis) (Antibody to)
Alternative technique antibodies
Alternative to gene target TPX2, microtubule-associated, homolog (Xenopus laevis), C20orf1 and C20orf2 and DIL-2 and DIL2 and FLS353 and GD:C20orf1 and HCA519 and HCTP4 and p100 and REPP86, TPX2 and IDBG-63816 and ENSG00000088325 and 22974, protein kinase binding, nuclei, Tpx2 and IDBG-209892 and ENSMUSG00000027469 and 72119, BT.28741 and IDBG-641544 and ENSBTAG00000018775 and 507226