Caspase-5 Substrate WEHD-pNA

  • Catalog number
    1102-1000
  • Price
    Please ask
  • Size
    1000 assays
  • Alternative_name
    Ac-WEHD-pNA, Caspase-5 Substrate, Colorimetric
  • Description
    Ready-to-use colorimetric substrate for caspase-5 and related caspases that recognize the amino acid sequence WEHD. Caspase-5 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l = 400 nm) after cleaved from the peptide substrate WEHD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economic alternative for researchers who perform large volume of caspase assays.
  • Structure Available
    No
  • Peptide sequence
    Ac-Trp-Glu-His-Asp-pNA
  • Salt Form
    No
  • Molecular Formula
    C₃₄H₃₇N₉O₁₁
  • Molecular Weight
    747.7
  • Cell Permeable
    No
  • Purity
    >99% by HPLC
  • Handling
    Protect from light and moisture
  • Tag Line
    A caspase-5 substrate
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • PubChem CID
    44135315
  • SMILES
    CC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCC(=O)O)C(=O)NC(CC3=CN=CN3)C(=O)NC(CC(=O)O)C(=O)NC4=CC=C(C=C4)[N+](=O)[O-]
  • InChi
    InChI=1S/C34H37N9O11/c1-18(44)38-26(12-19-15-36-24-5-3-2-4-23(19)24)33(51)40-25(10-11-29(45)46)31(49)41-27(13-21-16-35-17-37-21)34(52)42-28(14-30(47)48)32(50)39-20-6-8-22(9-7-20)43(53)54/h2-9,15-17,25-28,36H,10-14H2,1H3,(H,35,37)(H,38,44)(H,39,50)(H,40,51)(H,41,49)(H,42,52)(H,45,46)(H,47,48)
  • InChi Key
    FDGCMTAKGVLJGO-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Additional description
    Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
MeSH Data
  • Name
  • Concept
    Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
  • Tree numbers
    • E05.599.495
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