Caspase-5 Substrate WEHD-pNA
-
Catalog number1102-1000
-
PricePlease ask
-
Size1000 assays
-
-
Alternative_nameAc-WEHD-pNA, Caspase-5 Substrate, Colorimetric
-
DescriptionReady-to-use colorimetric substrate for caspase-5 and related caspases that recognize the amino acid sequence WEHD. Caspase-5 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l = 400 nm) after cleaved from the peptide substrate WEHD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economic alternative for researchers who perform large volume of caspase assays.
-
Structure AvailableNo
-
Peptide sequenceAc-Trp-Glu-His-Asp-pNA
-
Salt FormNo
-
Molecular FormulaC₃₄H₃₇N₉O₁₁
-
Molecular Weight747.7
-
Cell PermeableNo
-
Purity>99% by HPLC
-
HandlingProtect from light and moisture
-
Tag LineA caspase-5 substrate
-
Storage Condition-20°C
-
Shipping Conditiongel pack
-
Shelf Life12 months
-
PubChem CID44135315
-
SMILESCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCC(=O)O)C(=O)NC(CC3=CN=CN3)C(=O)NC(CC(=O)O)C(=O)NC4=CC=C(C=C4)[N+](=O)[O-]
-
InChiInChI=1S/C34H37N9O11/c1-18(44)38-26(12-19-15-36-24-5-3-2-4-23(19)24)33(51)40-25(10-11-29(45)46)31(49)41-27(13-21-16-35-17-37-21)34(52)42-28(14-30(47)48)32(50)39-20-6-8-22(9-7-20)43(53)54/h2-9,15-17,25-28,36H,10-14H2,1H3,(H,35,37)(H,38,44)(H,39,50)(H,40,51)(H,41,49)(H,42,52)(H,45,46)(H,47,48)
-
InChi KeyFDGCMTAKGVLJGO-UHFFFAOYSA-N
-
MSDS AvailableYes
-
Additional descriptionHuman and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
-
Gene target
-
Short nameCaspase-5 Substrate WEHD-pNA
-
Alternative namecaspase-5 Substrate WEHD-pNA
-
MeSH Data
-
Name
-
ConceptScope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
-
Tree numbers
- E05.599.495