Baricitinib phosphate

  • Catalog number
    2841-10
  • Price
    Please ask
  • Size
    10 mg
  • Alternative_name
    2-[1-Ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile, phosphoric acid; NCB 028050;LY 3009104;INCB028050;LY3009104;LY-3009104;INCB-028050
  • Description
    Baricitinib phosphate is a selective JAK1 and JAK2 inhibitor with IC₅₀ values of 5.9 nM and 5.7 nM, respectively. Baricitinib is ~70 and ~10-fold selective versus JAK3 and Tyk2, with no inhibition to c-Met and Chk2.
  • CAS Number
    1187595-84-1
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₆H₂₀N₇O₆PS
  • Molecular Weight
    469.41
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (~ 1 mg/ml)
  • Handling
    Protect from air and moisture
  • Tag Line
    A potent and selective JAK1 and JAK2 inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    44231848
  • SMILES
    CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
  • InChi
    InChI=1S/C16H17N7O2S.H3O4P/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14;1-5(2,3)4/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20);(H3,1,2,3,4)
  • InChi Key
    FBPOWTFFUBBKBB-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Baricitinib phosphate
  • Alternative name
    Baricitinib phosphate
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