Interleukin-8 (IL-8) is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. IL-8 and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.
CXCL8, C-X-C motif chemokine 8, IL-8, NAF, GCP1, LECT, LUCT, NAP1, CXCL8, GCP-1, LYNAP, MDNCF, MONAP, NAP-1
Antibody is purified by protein A affinity chromatography.
Ab raised in
Ni-NTA purified recombinant human IL-8 expressed in E.Coli. strain BL21 (DE3).
Western Blot:1:500 - 1,000ELISA:1,000 - 2,000.Determining optimal working dilutions by titration test.
Suspention, pH, azide
Purified antibody in PBS containing 0.03% sodium azide
IL-8 monoclonal antibody can be stored at -20 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.