anti-TRIM5 delta Antibody

  • Catalog number
    3241
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    TRIM5 delta Antibody: TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has five alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. Expression of TRIM5a; variants from humans, rhesus monkeys, and African green monkeys enabled resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies. The TRIM5δ isoform has been shown to colocalize with the topoisomerase I-interacting proteins BTBD1 and BTBD2 in punctate or elongated cytoplasmic bodies in several mouse and human cells where it appears to serve as a scaffold for the assembly of endogenous BTBD proteins. TRIM5δ also exhibits autoubiquitination activity in a RING finger- and UbcH5B-dependent manner.
  • Gene names
    TRIM5 delta Antibody: RNF88, TRIM5alpha, RNF88, Tripartite motif-containing protein 5, RING finger protein 88
  • Antibodie s label
    unlabelled serum
  • Purity
    TRIM5 delta Antibody is affinity chromatography purified via peptide column.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Antigen
    TRIM5 delta antibody was made against a synthetic peptide corresponding to 13 amino acids near the carboxy terminus of human TRIM5 delta.
  • Immuno application
    ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
  • Antibody advice
    TRIM5 delta antibody can be used for detection of TRIM5 delta by Western blot at 2 ug/mL. A band at approximately 25 kDa can be detected. Antibody can also be used for immunohistochemistry starting at 1 ug/mL. For immunofluorescence start at 10 ug/mL.
  • Suspention pH azide
    TRIM5 delta Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    TRIM5 delta antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human
  • Omim nr
    15011946
  • Ncbi nr
    NP_149084
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    85363
  • GENE symbol
    TRIM5
  • Antigene name
    tripartite motif-containing 5
  • Source
    Homo sapiens
  • Protein nr
    Q9C035
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    TRIM5   delta  
  • Gene symbol
    TRIM5
  • Short name
    anti-TRIM5 delta Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toTRIM5 delta (antibody to-)
  • Alternative technique
    antibodies
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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