PAG1 Polyclonal Antibody

• Catalog number
  CAC07686
• Price
  Please ask
• Size
  50 μg

• Other name
  Phosphoprotein associated with glycosphingolipid-enriched microdomains 1,Csk-binding protein,Transmembrane adapter protein PAG,Transmembrane phosphoprotein Cbp,PAG1,CBP,PAG
• Immunogen
  Recombinant human Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 protein (97-432AA)
• Verified reactivity
  Human, Mouse
• Verified applications
  ELISA,WB,IHC,IF. Recommended dilution:WB:1:2000-1:5000,IHC:1:20-1:200,IF:1:50-1:200
• Raised in
  Rabbit
• Clonality
  Polyclonal
• Protein number
  Q9NWQ8
• Gene number
  Please refer to GenBank
• NCBI number
  Please refer to NCBI
• Purity
  Protein G purified, >95%
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  3-7 business days
• Supplementary information
  Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Properties
  If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  PAG1  
• Gene symbol
  PAG1
• Short name
  PAG1 Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  Unconjugated
• Alternative name
  phosphoprotein associated with glycosphin this GO lipid microdomains 1 polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  phosphoprotein associated with glycosphin this GO lipid microdomains 1, PAG1 and IDBG-26542 and ENSG00000076641 and 55824, SH2 domain binding, Plasma membranes, Pag1 and IDBG-131044 and ENSMUSG00000027508 and 94212, PAG1 and IDBG-644850 and ENSBTAG00000014026 and 614460

Gene info

• Identity
  HGNC:30043
• Gene
  PAG1
• Long gene name
  phosphoprotein membrane anchor with glycosphingolipid microdomains 1
• Synonyms gene name
  • phosphoprotein associated with glycosphingolipid microdomains 1
• Synonyms
  • PAG
  • CBP
• Synonyms name
  • Csk-binding protein
  • transmembrane adaptor protein PAG
• GenBank acession
  • AF240634
• Locus
  8q21.13
• Discovery year
  2005-04-25
• Entrez gene record
  55824
• Pubmed identfication
  • 10790433
• RefSeq identity
  • NM_018440
• VEGA ID
  OTTHUMG00000164592

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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