Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor/M-CSF R/CSF1R/CD115(C-6His)

  • Catalog number
    CP66-500
  • Price
    Please ask
  • Size
    500 ug
  • Description
    Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor is produced by our Mammalian expression system and the target gene encoding Ile20-Pro517 is expressed with a 6His tag at the C-terminus.
  • Species reactivity
    Human
  • Origin
    Human cells
  • Peptide sequence
    IPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSVDVNFDVFLQHNNTKLAIPQQSDFHNNRYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNLKVMVEAYPGLQGFNWTYLGPFSDHQPEPKLANATTKDTYRHTFTLSLPRLKPSEAGRYSFLARNPGGWRALTFELTLRYPPEVSVIWTFINGSGTLLCAASGYPQPNVTWLQCSGHTDRCDEAQVLQVWDDPYPEVLSQEPFHKVTVQSLLTVETLEHNQTYECRAHNSVGSGSWAFIPISAGAHTHPPDEFLFTPHHHHHH
  • Estimated molecular weight
    55,9 kDa
  • Protein purity
    Greater than 95% as determined by reducing SDS-PAGE.
  • Endotoxin level
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
  • Shipping condition
    Ambient/Room Temperature
  • Package form
    Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
  • Storage conditions
    Lyophilized protein should be stored at below -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at below -20°C for 3 months.
  • Reconstitution conditions
    See included datasheet or contact us for more information.
  • UniProt number
    P07333
  • Other related products
  • Additional description
    Colonies can be formed by stimulating factors or recombinant GM-CSF and CSFs activity expressed in Units compared to a standard. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    Macrophage   Colony-stimulating   Factor   Receptor/M-CSF   R/CSF1R/CD115   C-6His  
  • Gene symbol
    CSF1, CSF1R, CPT1B, CSF2, IRAK3, PGAM2, CYP20A1, USP16, CYB5B, H3C14
  • Short name
    Recombinant Macrophage Colony-stimulating Factor 1 Receptor/M-CSF R/CSF1R/CD115(C-6His)
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Human, Humans
  • Alternative name
    Recombinant Human M-CSF R(C-6His)
  • Alternative technique
    rec
  • Alternative to gene target
    colony stimulating factor 1 receptor, C-FMS and CD115 and CSF-1R and CSFR and FIM2 and FMS and HDLS and M-CSF-R, CSF1R and IDBG-53268 and ENSG00000182578 and 1436, transferase activity, Cell surfaces, Csf1r and IDBG-150998 and ENSMUSG00000024621 and 12978, CSF1R and IDBG-646265 and ENSBTAG00000012771 and 509418
Gene info
Gene info
  • Identity
    HGNC:2433
  • Gene
    CSF1R
  • Long gene name
    colony stimulating factor 1 receptor
  • Synonyms gene
  • Synonyms gene name
    • McDonough feline sarcoma viral (v-fms) oncogene homolog
  • Synonyms
  • GenBank acession
  • Locus
    5q32
  • Discovery year
    2001-06-22
  • Entrez gene record
    1436
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Immunoglobulin like domain containing
    • Receptor tyrosine kinases
    • CD molecules
  • VEGA ID
    OTTHUMG00000130050
Gene info
Gene info
Gene info
  • Identity
    HGNC:17020
  • Gene
    IRAK3
  • Long gene name
    interleukin 1 receptor associated kinase 3
  • Synonyms gene name
    • interleukin-1 receptor-associated kinase 3
  • Synonyms
  • GenBank acession
  • Locus
    12q14.3
  • Discovery year
    2002-07-17
  • Entrez gene record
    11213
  • Pubmed identfication
  • Classification
    • MicroRNA protein coding host genes
  • VEGA ID
    OTTHUMG00000169002
Gene info
  • Identity
    HGNC:8889
  • Gene
    PGAM2
  • Long gene name
    phosphoglycerate mutase 2
  • Synonyms gene name
    • phosphoglycerate mutase 2 (muscle)
  • Synonyms
  • Locus
    7p13
  • Discovery year
    1989-06-30
  • Entrez gene record
    5224
  • Classification
    • Phosphoglycerate mutases
    • Bisphosphoglycerate phosphatases
  • VEGA ID
    OTTHUMG00000155355
Gene info
  • Identity
    HGNC:20576
  • Gene
    CYP20A1
  • Long gene name
    cytochrome P450 family 20 subfamily A member 1
  • Synonyms gene name
    • cytochrome P450, family 20, subfamily A, polypeptide 1
  • Synonyms
  • GenBank acession
  • Locus
    2q33.2
  • Discovery year
    2003-03-20
  • Entrez gene record
    57404
  • RefSeq identity
  • Classification
    • Cytochrome P450 family 20
  • VEGA ID
    OTTHUMG00000132854
Gene info
  • Identity
    HGNC:12614
  • Gene
    USP16
  • Long gene name
    ubiquitin specific peptidase 16
  • Synonyms gene name
    • ubiquitin specific protease 16
  • Synonyms
  • GenBank acession
  • Locus
    21q21
  • Discovery year
    1999-07-09
  • Pubmed identfication
  • Classification
    • Ubiquitin specific peptidases
  • VEGA ID
    OTTHUMG00000078802
Gene info
Gene info
MeSH Data
  • Name
    Colony-Forming Units Assay
  • Concept
    Scope note: A cytologic technique for measuring the functional capacity of stem cells by assaying their activity.
  • Tree numbers
    • E01.370.225.500.383
    • E05.200.500.383
    • E05.242.383
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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Recombinant Macrophage Colony stimulating Factor 1 Receptor
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