OVA Conjugated Toll Like Receptor 4 (TLR4)
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Catalog number
CPA753Hu21
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Price
Please ask
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Size
1mg
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Source
Protein conjugation
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Predicted Molecular Mass KD
NA
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Accurate Molecular Mass KD
NA
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Organism species
Homo sapiens (Human)
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Item Name
Toll Like Receptor 4
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Alternative Names
CD284; TOLL; HToll
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Research Area
Signal transduction;Enzyme & Kinase;Tumor immunity;Infection immunity;Pulmonology;
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Buffer Formulation
PBS, pH7.4.
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Traits
Freeze-dried powder
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Purity
> 90%
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Protein length
Gly420-Lys435
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Tag
N-terminal His Tag
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Expression System
Protein conjugation
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Application
Immunogen; SDS-PAGE; WB.
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Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
TLR4
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Short name
OVA Conjugated Toll Like Receptor 4 (TLR4)
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Technique
antibody Conjugates
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Host
Protein conjugation
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Species
Homo sapiens (Human)
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Alternative name
OVA coupled Toll Like Receptor 4 (toll-like receptor 4)
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Alternative to gene target
toll-like receptor 4, ARMD10 and CD284 and TLR-4 and TOLL, TLR4 and IDBG-82738 and ENSG00000136869 and 7099, protein binding, Cell surfaces, Tlr4 and IDBG-156729 and ENSMUSG00000039005 and 21898, TLR4 and IDBG-638758 and ENSBTAG00000006240 and 281536
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Gene info
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Identity
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Gene
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Long gene name
toll like receptor 4
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-06-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Toll like receptors
- CD molecules
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VEGA ID
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Locus Specific Databases
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