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SHOC2 Antibody ALEXA FLUOR

SHOC2 Antibody ALEXA FLUOR is available 5 times from Bioss primary conjugated antibodies. alexa fluor labs

bs-7934R-A350 | SHOC2 Antibody, ALEXA FLUOR 350 size: 100ul | 446.16 USD

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bs-7934R-A488 | SHOC2 Antibody, ALEXA FLUOR 488 size: 100ul | 446.16 USD

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bs-7934R-A555 | SHOC2 Antibody, ALEXA FLUOR 555 size: 100ul | 446.16 USD

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bs-7934R-A594 | SHOC2 Antibody, ALEXA FLUOR 594 size: 100ul | 446.16 USD

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bs-7934R-A647 | SHOC2 Antibody, ALEXA FLUOR 647 size: 100ul | 446.16 USD

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Category Conjugated Primary Antibodies
Host Organism Rabbit (Oryctolagus cuniculus)
Target Antigen SHOC2
Specificity This is a highly specific antibody against SHOC2.
Modification Unmodified
Modification Site None
Clonality Polyclonal
Clone Polyclonal antibody
Concentration 1ug per 1ul
Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHOC2/Sur8
Gene ID Number 8036
Tested applications IF(IHC-P)
Recommended dilutions IF(IHC-P)(1:50-200)
Crossreactivity Human, Mouse, Rat
Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) . NSLAH children display macrocephaly, high forehead, hypertelorism, palpebral ptosis, low-set and posteriorly rotated ears, short and webbed neck and pectus anomalies. Affected subjects also have easily pluckable, sparse, thin and slow-growing hair.
Purification Purified by Protein A.
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Synonyms Leucine-rich repeat protein SHOC-2; Leucine-rich repeat protein SHOC-2; Ras-binding protein Sur-8; KIAA0862; Leucine-rich repeat protein SHOC-2; Protein soc-2 homolog; Protein Sur-8 homolog; SHOC2; SHOC2_HUMAN.
Gene targetSHOC2
Short name Anti-SHOC2
Technique Antibody
Isotype Immunoglobulin G (IgG)
Alternative technique antibodies
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SHOC2 Antibody ALEXA FLUOR - Gentaur.com
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