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Products_type
Antibody
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Products_short_name
[Activating Transcription Factor 4]
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Products_name_syn
[Anti -Activating Transcription Factor 4, phosphorylated (Ser245) (ATF4, Tax-responsive Enhancer Element B67)]
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Other_names
[activating transcription factor 4; activating transcription factor 4; activating transcription factor 4b2]
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Other_gene_names
[atf4b2; sb:eu681; wu:fb08f07; zgc:171702]
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Clonality
Polyclonal
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Reactivity
Human
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Specificity
Detects endogenous levels of ATF4 only when phosphorylated at serine 245.
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Purity
Affinity Purified Purified by immunoaffinity chromatography.
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Form
Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.
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Storage_stability
For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
Immunohistochemistry (IHC)
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
