Cyclosporine A
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Catalog number1522-100
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PricePlease ask
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Size100 mg
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Alternative_nameAntibiotic S 7481F1, Cyclosporine
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DescriptionA fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B.
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CAS Number59865-13-3
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₆₂H₁₁₁N₁₁O₁₂
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Molecular Weight1202.6
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Cell PermeableYes
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Purity>99%
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SolubilitiesDMSO and EtOH
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HandlingProtect from light and air
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Tag LineAn immunosuppressant
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Storage Condition+4°C
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Shipping ConditionRT
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Shelf Life12 months
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MDL NumberMFCD00274558
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PubChem CID5284373
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SMILESCCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
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InChiInChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59 (82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1
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InChi KeyPMATZTZNYRCHOR-CGLBZJNRSA-N
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MSDS AvailableYes
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Gene target
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Short nameCyclosporine A
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Alternative nameCyclosporine A
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