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Also known as
Defensin
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Other names
embryo surrounding region6; N/A; embryo surrounding region6; defensin; GRMZM2G048353; embryo surrounding region6; N/A
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
esr6; N/A; esr-6; esr6a; N/A
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Gene name synonims
esr6; N/A; esr-6; esr6a; N/A
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Other gene names
esr6; N/A; esr-6; esr6a; N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1 for MAbs D1F4, D1C9, D1H5, D2C6, D2B3, D3A6, D3D3, A6D4 IgG2a for MAb B1G8 IgG2b for MAbs B4B6, B3C5 IgM for MAb B1F7
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Clone
D1F4, D1C9, D1H5, D2C6, D2B3, D3A6, D3D3, B1F7, B4B6; New MAbs: A6D4, B3C5, B1G8
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Host organism
N/A
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Species reactivity
N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
MAbs D1F4, D1C9, D1H5, D2C6, D2B3, D3A6, D3D3 all react with cyclic human defensins 1, 2 and 3 (NP1, NP2 and NP3, respectively). MAbs D1F4, D1C9, D1H5, D2C6, D2B3, D3A6, D3D3 all recognize also linear human defensins 1-3 that are parts of recombinant fuses. MAbs B1F7, A6D4, B3C5, B1G8 react with defensin 5. MAb B4B6 reacts with defensin 6.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Chromatography on protein G Sepharose
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Form Appearance
PBS, pH 7.4, 0.1 % sodium azide (NaN3)
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius.
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Tested applications
N/A
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. human, mouse or other beta β- and alpha α- defensins are expressed by neutrophils ( α- ), lymphocytes and epithelial cells. DEFA DEFB genes defend the host against pathogens. GENTAUR supplies anti-defensins, monclonals, polyclonals antisera and recombinant DEFs or peptides of defensin.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
