PLGF, murine recombinant

• Catalog number
  4743-1000
• Price
  Please ask
• Size
  1 mg

• Synonyms
  Placenta Growth Factor
• Alternative_names
  Placenta Growth Factor
• Description
  A key molecule in angiogenesis and vasculogenesis
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Purity
  ≥95%
• Biological activity
  Determined by its ability to chemoattract human monocytes of using a concentration range of 0.5-10 ng/ml.
• Results
  0.5-10 ng/ml
• Molecular Weight
  32.6 kDa
• Storage Temp
  -20°C
• Shipping
  Blue ice
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Sterile filtered and lyophilized with no additives
• Reconstitution Instructions
  Reconstitute the protein in sterile 20 mM acetic acid to a concentration of 0.1-1.0 ug/ul. The solution can then be diluted into other aqueous buffer
• Background Information
  PLGF (also called Placenta Growth Factor, PIGF, PGF) is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PLGF is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant mouse PLGF is a disulfide-linked homodimer containing two 142 amino acid polypeptide chains.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  PLGF   murine  
• Gene symbol
  PGF
• Short name
  PLGF, murine recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  PLGF, murine Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:8893
• Gene
  PGF
• Long gene name
  placental growth factor
• Synonyms gene
  • PGFL
• Synonyms gene name
  • placental growth factor-like
  • placental growth factor, vascular endothelial growth factor-related protein
• Synonyms
  • PlGF-2
  • SHGC-10760
  • D12S1900
  • PIGF
  • PLGF
  • PlGF
• Synonyms name
  • placenta growth factor
• GenBank acession
  • S72960
• Locus
  14q24.3
• Discovery year
  1994-01-14
• Entrez gene record
  5228
• Pubmed identfication
  • 7681160
• RefSeq identity
  • NM_002632
• Classification
  • VEGF family
• VEGA ID
  OTTHUMG00000171496

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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