CD35/ CR1 Antibody

• Catalog number
  GEN438337
• Price
  Please ask
• Size
  100ug

• Also known as
  CD35
• Other names
  complement receptor type 1 isoform F; Complement receptor type 1; complement receptor type 1; CD35 antigen; C3b/C4b receptor; C3-binding protein; Knops blood group antigen; complement component (3b/4b) receptor 1 (Knops blood group); C3b/C4b receptor; CD_antigen: CD35
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  CR1
• Gene name synonims
  N/A
• Other gene names
  CR1; CR1; KN; C3BR; C4BR; CD35; C3BR
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1, kappa
• Clone
  E11
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens), Baboon, Cynomolgus Monkey, Rhesus Monkey.; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD35   CR1  
• Gene symbol
  CR1
• Short name
  CD35/ CR1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Anti-CD35/ CR1
• Alternative technique
  antibodies
• Alternative to gene target
  complement component (3b/4b) receptor 1 (Knops blood group), C3BR and C4BR and CD35 and KN, CR1 and IDBG-106358 and ENSG00000203710 and 1378, complement component C3b receptor activity, Cell surfaces

Gene info

• Identity
  HGNC:2334
• Gene
  CR1
• Long gene name
  complement C3b/C4b receptor 1 (Knops blood group)
• Synonyms gene name
  • complement component (3b/4b) receptor 1, including Knops blood group system
  • complement component (3b/4b) receptor 1 (Knops blood group)
  • complement component 3b/4b receptor 1 (Knops blood group)
• Synonyms
  • CD35
  • KN
• GenBank acession
  • Y00816
• Locus
  1q32.2
• Discovery year
  2001-06-22
• Entrez gene record
  1378
• Pubmed identfication
  • 1708809
• RefSeq identity
  • NM_000573
• Classification
  • Blood group antigens
  • Complement system regulators and receptors
  • CD molecules
  • Sushi domain containing
• VEGA ID
  OTTHUMG00000036311
• Locus Specific Databases
  • Blood Group Antigen Mutation Database
  • LRG_814

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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