HSP90 Antibody ( AC16)
-
Catalog numberMA1051
-
PricePlease ask
-
Size0,1 mg
-
-
Target antigenHSP90
-
ClonalityMonoclonal antibody
-
CloneAC-16
-
Raised inmice
-
Type of the antibodyIgG2b monoclonal antibody
-
Product formfreeze-dried
-
Reacts with speciesHuman, mouse, rabbit, rat
-
AnalysesWB
-
ImmunogenHeat shock protein 90(HSP90) from the water mold Achlya ambisexualis.
-
Product configurationMouse ascites fluid, 1.2% Na acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
-
PurificationAscites
-
SolubilizationThe powdered antibody should be dissolved in 1ml of PBS buffer to achieve final concentration of 100ug/ml.
-
Storage condtionsKeep the HSP90 Antibody ( AC16)at minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
-
TipsThe HSP90 Antibody ( AC16) did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
-
BackgroundHeat Shock Protein 90(HSP70) exists in multiple forms in mammalian cells. It has a unique 30-amino acid N terminus instead of the 223-amino acid ATP/geldanamycin-binding domain found at the N terminus of full-length HSPCA, which contains 732 amino acids. Functional proteomic screens reveal an essential extracellular role for hsp90-alpha in cancer cell invasiveness.
-
Related articles1. Ozawa, K.; Murakami, Y.; Eki, T.; Soeda, E.; Yokoyama, K. : Mapping of the gene family for human heat-shock protein 90-alpha to chromosomes 1, 4, 11, and 14. Genomics 12: 214-220, 1992. 2. Eustace, B. K.; Sakurai, T.; Stewart, J. K.; Yimlamai, D.; Unger, C.; Zehetmeier, C.; Lain, B.; Torella, C.; Henning, S. W.; Beste, G.; Scroggins, B. T.; Neckers, L.; Ilag, L. L.; Jay, D. G. : Functional proteomic screens reveal an essential extracellular role for hsp90-alpha in cancer cell invasiveness. Nature Cell Biol. 6: 507-514, 2004.
-
Gene NameHSP90AA1; HSP90AB1
-
Protein NameHeat shock protein HSP 90-alpha; Heat shock protein HSP 90-beta
-
Gene Full Nameheat shock protein 90kDa alpha(cytosolic), class A member 1; heat shock protein 90kDa alpha(cytosolic), class B member 1
-
SynonymsHSP90A|HSPC1|HSPCA|HSP90B|HSPC2|HSPCB
-
Uniprot IDHuman(P07900), Mouse(P07901), Rat(P82995), Human(P08238), Mouse(P11499), Rat(P34058)
-
Entrez GeneIDHuman(3320), Mouse(15519), Rat(299331), Human(3326), Mouse(15516), Rat(301252)
-
PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolHSP90AA1
-
Short nameHSP90 Antibody ( AC16)
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
Alternative nameHSP90 (antibody to-) ( AC16)
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameheat shock protein 90 alpha family class A member 1
-
Synonyms gene
-
Synonyms gene name
- heat shock 90kD protein 1, alpha
- heat shock 90kDa protein 1, alpha
- heat shock protein 90kDa alpha (cytosolic), class A member 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1990-06-27
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Heat shock 90kDa proteins
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data