Filters
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing

IL-2 Receptor α Human Recombinant

IL-2 Receptor α Human Recombinant is available 2 times from Biovision labs

7100-10 | IL-2 Receptor α, Human Recombinant size: 10 ug | 212.27 USD

Loading

7100-50 | IL-2 Receptor α, Human Recombinant size: 50 ug | 671.23 USD

Loading
Synonyms soluble IL-2 receptor, TAC-antigen, CD25 antigen
Alternative_names soluble IL-2 receptor, TAC-antigen, CD25 antigen
Description A receptor present on immune cells like lymphocytes, which binds and responds to IL-2 cytokine
Recombinant Yes
Source (BTI-Tn-5B1-4) Hi-5 Insect Cells
Purity by SDS-PAGE ≥98%
Assay SDS-PAGE
Endotoxin Level< 0.1 ng/ug of protein (
Activity (Specifications/test method) Determined by its ability to increase the proliferation effect of IL-2 in mouse CTLL-2 cells. In the presence of 1 ng/ml of recombinant IL-2, the expected ED50 for this effect is between 0.5-1.5 ug/ml.
Biological activity Determined by its ability to increase the proliferation effect of IL-2 in mouse CTLL-2 cells. In the presence of 1 ng/ml of recombinant IL-2, the expected ED50 for this effect is between 0.5-1.5 ug/ml.
Molecular Weight 24.8 kDa (31 kDa on SDSPAGE due to glycosylation)
Storage Temp. -20°C
Shipping Gel Pack
Shelf Life 12 months
Appearance Lyophilized powder
Physical form description Sterile filtered through a 0.2 micron filter. Lyophilized from 1x PBS
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in 1x PBS pH 7.2 to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Background Information The IL-2 receptor system consists of three non-covalently linked subunits termed IL-2Rα, IL-2Rβ, and IL-2Rγ. The IL-2Rα is a type I transmembrane protein consisting of a 219 amino acid extracellular domain, a 19 amino acid transmembrane domain and a 13 amino acid intracellular domain, which is not involved in the transduction of IL-2 signals. Proteolytic processing of IL-2Rα releases the entire extracellular domain of IL-2Rα thereby generating a 219 amino acid soluble protein called soluble IL-2Rα (sIL-2Rα). The homodimeric form binds IL-2 (KD=10mM) and facilitates IL-2 signaling. The secreted sIL-2Rα is expressed on leukemia cells, lymphoma cells, newly activated T and B cells, as well as on approximately 10% of NK cells. Recombinant human sIL-2Rα is a 24.8 kDa protein containing 219 amino acid residues consisting of only the extracellular domain of IL-2Rα. Due to glycosylation, IL-2Rα has an approximate molecular weight of 31 kDa based on SDSPAGE gel and Mass Spectrometry.
Amino acid sequence ELCDDDPPEI PHATFKAMAY KEGTMLNCEC KRGFRRIKSG SLYMLCTGNS SHSSWDNQCQ CTSSATRNTT KQVTPQPEEQ KERKTTEMQS PMQPVDQASL PGHCREPPPW ENEATERIYH FVVGQMVYYQ CVQGYRALHR GPAESVCKMT HGKTRWTQPQ LICTGEMETS QFPGEEKPQA SPEGRPESET SCLVTTTDFQ IQTEMAATME TSIFTTEYQ
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional description The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetIL-2 Receptor
Short name IL-2 Receptor α, Recombinant
Technique Recombinant
Species Humans
Alternative name Interleukin-2 Receptor α, H. sapiens recombinant
Alternative technique rec
Similar products
Cyclin D1 Blocking Peptide Suppplier: Abbexa
Price: 829.88 USD
Assay kit for Mouse CST complex subunit ELISA Suppplier: BlueGen ELISAs
Price: 703.19 USD
PCDH1 siRNA Suppplier: Abbexa
Price: 690.41 USD
GHRH siRNA Suppplier: Abbexa
Price: 690.41 USD
Human Acrosin ELISA Kit Suppplier: SAB ELISA KIT
Price: 663.67 USD
Anti-ADAMTS8 (Polyclonal), ALEXA Fluor 594 Suppplier: Bioss Polyclonal Antibodies
Price: 568.36 USD
Human Glycoprotein ELISA Kit Suppplier: BT-Laboratory
Price: 430.05 USD
HOXB13 Lentiviral Vector Human pLenti GIII Suppplier: ABM lentivectors
Price: 374.84 USD
Voltage Dependent Channel Protein Suppplier: MyBioSource
Price: 5.81 USD
Trypsin 1.2 3 PRSS1.2 3 Suppplier: MyBioSource
Price: 5.81 USD
Protein A Poly HRP40 Suppplier: MyBioSource
Price: 5.81 USD
Chicken Lipoma- preferred partner homolog, LPP ELISA KIT Suppplier: Lifescience Market
Price: 1 078.61 USD
[5-Cyano-6-methylthymin-1-yl]acetic acid Suppplier: SFC
Price: 0.00 USD
1-[2-(Diethylamino)ethyl]piperazine Suppplier: SFC
Price: 0.00 USD
Ask
Ajax processing
Close
IL-2 Receptor α Human Recombinant - Gentaur.com
Filters
EU:+32-(0)1-658-90-45 US:+1-(408)780-0908 [email protected]
  • IL-2
  • Receptor
Back
Contact us
Ajax processing
Close
Chat with gentaur.com employee