IL-1 alpha Recombinant Protein

• Catalog number
  40-240
• Price
  Please ask
• Size
  0.002 mg, 0.01 mg

• About recombinant protein
  IL-1β is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant human IL-1α is an 18.0 kDa protein containing 159 amino acid residues.
• Other name of the recombinant
  IL1, IL-1A, IL1F1, IL1-ALPHA, Interleukin-1 alpha, Hematopoietin-1, IL-1 alpha
• Recombinant in
  E. coli
• SEQUENCE
  SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA
• Activity
  The ED50 was determined by the dose - dependent stimulation of murine D10S cells is ≤ 0.001 ng/mL, corresponding to a specific activity of ≥ 1 x 109 units/mg.
• Keep at
  The lyophilized IL-1 alpha recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-1 alpha is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-1 alpha recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  27894330
• Accession nr
  NP_000566.3
• Pureity
  Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  3552
• Gene name
  interleukin 1, alpha
• Source
  Homo sapiens
• Uniprot
  P01583
• Pictures of recombinant
• Rec pdf
• Description
  The IL-1 alpha Recombinant Protein is a α- or alpha protein sometimes glycoprotein present in blood.
• Gene
  The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  IL-1   alpha   Protein  
• Gene symbol
  IL1A
• Short name
  IL-1 alpha Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Interleukin-1 a Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:5991
• Gene
  IL1A
• Long gene name
  interleukin 1 alpha
• Synonyms gene
  • IL1
• Synonyms
  • IL1F1
  • IL-1A
  • IL1-ALPHA
• Synonyms name
  • preinterleukin 1 alpha
  • hematopoietin-1
  • pro-interleukin-1-alpha
• GenBank acession
  • M28983
• Locus
  2q14.1
• Discovery year
  2001-06-22
• Entrez gene record
  3552
• Pubmed identfication
  • 8188271
  • 2989698
• RefSeq identity
  • NM_000575
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131315

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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