anti-EVER2 Antibody

• Catalog number
  4605
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  EVER2 Antibody: Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc.
• Gene names
  EVER2 Antibody: EV2, EVER2, EVIN2, Transmembrane channel-like protein 8, Epidermodysplasia verruciformis protein 2
• Antibodie s label
  unlabelled serum
• Purity
  EVER2 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  At least three isoforms of EVER2 are known to exist; this antibody will only recognize the larger isoform. EVER2 has no cross-reactivity to EVER1.
• Antigen
  EVER2 antibody was made against a 14 amino acid synthetic peptide from near the center of human EVER2.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  EVER2 antibody can be used for detection of EVER2 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  EVER2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  EVER2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  25527192
• Ncbi nr
  AAM44454
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  147138
• GENE symbol
  TMC8
• Antigene name
  transmembrane channel-like 8
• Source
  Homo sapiens
• Protein nr
  Q8IU68
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  EVER2  
• Gene symbol
  TMC8
• Short name
  anti-EVER2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toEVER2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:20474
• Gene
  TMC8
• Long gene name
  transmembrane channel like 8
• Synonyms gene
  • EVER2
• Synonyms gene name
  • epidermodysplasia verruciformis 2
• Synonyms
  • EVIN2
• GenBank acession
  • AY057380
• Locus
  17q25.3
• Discovery year
  2003-02-17
• Entrez gene record
  147138
• Pubmed identfication
  • 12426567
• Classification
  • Transmembrane channel like family
• VEGA ID
  OTTHUMG00000177436
• Locus Specific Databases
  • TMC8base: Mutation registry for Epidermodysplasia verruciformis (previously known as EVER2base)
  • LRG_119

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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