anti-WSB1 Antibody

• Catalog number
  8161
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  The WD repeat and SOCS box-containing 1 (WSB1, also known as SWIP1), is a member of the WD-protein subfamily (1). It contains six WD-repeats spanning most of the protein and an SOCS box in the C-terminus and expressed as multiple alternatively spliced isoforms (1,2). WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2 (3). Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis (4,5).
• Gene names
  WD repeat and SOCS box containing 1, SOCS box-containing WD protein SWiP-1, SWIP1, WD repeat and SOCS box-containing protein 1, WSB-1
• Antibodie s label
  unlabelled serum
• Purity
  WSB1 antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  WSB1 antibody is human specific.
• Antigen
  WSB1 antibody was made against a 16 amino acid peptide near the amino terminus of human WSB1.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  WSB1 antibody can be used for detection of WSB1 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  WSB1 antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  WSB1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
• Works with
  Human
• Omim nr
  18677720
• Ncbi nr
  NP_056441
• KDa
  Predicted: 46 kDa Observed: 46 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  26118
• GENE symbol
  WSB1
• Antigene name
  WD repeat and SOCS box containing 1
• Source
  homo sapiens
• Protein nr
  Q9Y6I7
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  WSB1  
• Gene symbol
  WSB1
• Short name
  anti-WSB1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toWSB1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:19221
• Gene
  WSB1
• Long gene name
  WD repeat and SOCS box containing 1
• Synonyms gene name
  • WD repeat and SOCS box-containing 1
• Synonyms
  • DKFZp564A122
  • DKFZp564B0482
  • SWIP1
• GenBank acession
  • AF069313
• Locus
  17q11.1
• Discovery year
  2004-02-20
• Entrez gene record
  26118
• Pubmed identfication
  • 10354473
  • 12076535
• RefSeq identity
  • NM_015626
• Classification
  • WD repeat domain containing
• VEGA ID
  OTTHUMG00000132293

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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