SLAMF6, human recombinant

• Catalog number
  7330-100
• Price
  Please ask
• Size
  100 ug

• Synonyms
  SLAM family member 6, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000
• Alternative_names
  SLAM family member 6, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000
• Description
  Potentiates T cell expansion in a CD28-independent manner
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥85%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per 1 microgram of protein
• Molecular Weight
  25.5 kDa (228 aa, 22-226 aa + His Tag), confirmed by MALDI-TOF.
• Storage Temp
  -80°C
• Shipping
  Dry Ice
• Shelf Life
  12 months
• Concentration
  1 mg/ml
• Appearance
  Liquid
• Physical form description
  1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, and 0.4 M Urea.
• Background Information
  SLAM family member 6, also known as SLAMF6, belongs to the SLAM family of immune cell receptors. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. SLAMF6 is expressed on NK-, T-, and B cells. It exhibits homotypic interactions and can associate with adaptor molecules such as SAP to modulate immune cell functions. Recombinant human SLAMF6 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Amino acid sequence
  MGSSHHHHHH SSGLVPRGSH MGSQSSLTPL MVNGILGESV TLPLEFPAGE KVNFITWLFN ETSLAFIVPH ETKSPEIHVT NPKQGKRLNF TQSYSLQLSN LKMEDTGSYR AQISTKTSAK LSSYTLRILR QLRNIQVTNH SQLFQNMTCE LHLTCSVEDA DDNVSFRWEA LGNTLSSQPN LTVSWDPRIS SEQDYTCIAE NAVSNLSFSV SAQKLCEDVK IQYTDTKM
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  SLAMF6  
• Gene symbol
  SLAMF6
• Short name
  SLAMF6, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  SLAMF6, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:21392
• Gene
  SLAMF6
• Long gene name
  SLAM family member 6
• Synonyms
  • KALI
  • NTBA
  • KALIb
  • Ly108
  • SF2000
  • NTB-A
  • CD352
• GenBank acession
  • AL832854
• Locus
  1q23.2-q23.3
• Discovery year
  2003-10-29
• Entrez gene record
  114836
• Pubmed identfication
  • 11489943
• RefSeq identity
  • NM_052931
• Classification
  • Ig-like cell adhesion molecule family
  • V-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000022729

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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