E3 ligase Ligand-Linker Conjugates 13 2g
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Catalog number
CS-7735-2g
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Price
Please ask
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Size
2g
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Alternative_Names
NA
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CAS
2010159-45-0
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Purity
>98%
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MWt
601.72
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Formula
C28H39N7O6S
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Solubility
DMSO : 50 mg/mL (83.10 mM; Need ultrasonic)
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Clinical_Information
No Development Reported
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Pathway
PROTAC
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Target
E3 Ligase Ligand-Linker Conjugate
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Description
FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
MeSH Data
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Name
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Concept
Scope note:
A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
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Tree numbers
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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