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Gene info
MYBPC2 Antibody: Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the fast-type isoform designated MYBPC2. Both the fast-type and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. MYBPC2 is typically required for strong contractions and functions under anaerobic conditions. It is more similar to the cardiac isoform (MYBPC3) than to the slow-type isoform (MYBPC1) in terms of pCa50-indexed force development, length-independent cooperativity and length dependent activation. It has been suggested that in cardiac and fast muscle MYBPC2 contributes to an internal load, possibly by binding to actin via its N-terminal region.
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Gene names
MYBPC2 Antibody: MYBPC, MYBPCF, Myosin-binding protein C, fast-type, C-protein, skeletal muscle fast isoform, Fast MyBP-C
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Antibodie s label
unlabelled serum
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Purity
MYBPC2 Antibody is affinity chromatography purified via peptide column.
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Ab raised in
Rabbit
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Type
Polyclonal
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Immunoglobulin
IgG
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Antigen
MYBPC2 antibody was made against a 15 amino acid synthetic peptide near the carboxy terminus of human MYBPC2.
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Immuno application
ELISA, Western Blot, immuno-histo-chemistry
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Antibody advice
MYBPC2 antibody can be used for detection of MYBPC2 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL.
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Suspention pH azide
MYBPC2 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
MYBPC2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Human, Mouse
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Omim nr
119592272
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Ncbi nr
EAW71866
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
4606
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GENE symbol
MYBPC2
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Antigene name
myosin binding protein C, fast type
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Source
Homo sapiens
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Protein nr
Q14324
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
MYBPC2
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Short name
anti-MYBPC2 Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody tomyosin binding protein C, fast classification (antibody to-)
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Alternative technique
antibodies
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Alternative to gene target
myosin binding protein C, fast type, MYBPC and MYBPCF, MYBPC2 and IDBG-64489 and ENSG00000086967 and 4606, structural constituent of muscle, Cytoplasm, Mybpc2 and IDBG-178931 and ENSMUSG00000038670 and 233199, MYBPC2 and IDBG-641047 and ENSBTAG00000020080 and
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