AZD6244

• Catalog number
  2234-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide; Selumetinib; ARRY-142886
• Description
  Cell-permeable. A potent, highly selective and non-ATP competitive inhibitor of mitogen-activated protein kinase kinase 1/2 (MEK1/2) (IC₅₀ = 14 nM/L against purified MEK1). Displays antineoplastic activity.
• CAS Number
  606143-52-6
• Structure Available
  Yes
• Molecular Formula
  C₁₇H₁₅BrClFN₄O₃
• Molecular Weight
  457.68
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from light and moisture
• Tag Line
  A potent and selective MEK1/2 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD11977472
• PubChem CID
  10127622
• PubChem CID Link
• SMILES
  CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
• InChi
  InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)
• InChi Key
  CYOHGALHFOKKQC-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  AZD6244  
• Short name
  AZD6244
• Alternative name
  AZD6244

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