PIMT Antibody / PCMT1

• Catalog number
  F53950-0.05ML
• Price
  Please ask
• Size
  0.05 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  PIMT / PCMT1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 1:1000-2000
• Intented use
  This PIMT antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  5110
• Uniprot
  P22061
• Purity
  Antigen affinity
• Description
  Catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl- terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein (By similarity).
• Immunogen
  A portion of amino acids 18-55 from the human protein was used as the immunogen for the PIMT antibody.
• Storage
  Aliquot the PIMT antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PIMT   PCMT1  
• Gene symbol
  PCMT1, TGS1
• Short name
  Anti- PIMT / PCMT1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to PIMT / PCMT1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8728
• Gene
  PCMT1
• Long gene name
  protein-L-isoaspartate (D-aspartate) O-methyltransferase
• Locus
  6q25.1
• Discovery year
  1992-09-11
• Entrez gene record
  5110
• Pubmed identfication
  • 1478665
  • 10343128
• Classification
  • 7BS protein methyltransferases
• VEGA ID
  OTTHUMG00000015794

Gene info

• Identity
  HGNC:17843
• Gene
  TGS1
• Long gene name
  trimethylguanosine synthase 1
• Synonyms gene
  • NCOA6IP
• Synonyms gene name
  • nuclear receptor coactivator 6 interacting protein
  • trimethylguanosine synthase homolog (S. cerevisiae)
• Synonyms
  • PIMT
• GenBank acession
  • AY028423
• Locus
  8q12.1
• Discovery year
  2001-12-19
• Entrez gene record
  96764
• Pubmed identfication
  • 11517327
  • 11983179
  • 19307714
• RefSeq identity
  • NM_024831
• Classification
  • 7BS DNA/RNA methyltransferases
• VEGA ID
  OTTHUMG00000164294

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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