PD-161570
-
Catalog numberP217490
-
PricePlease ask
-
Size2 mg
-
-
Chemical available in other sizesPlease inquire size and price
-
Stock availabilityIn Stock
-
Cas number192705-80-9
-
Chemical s molecular weight532.51
-
Chemical s main applicationsPD-161570 is a novel FGF-1 receptor tyrosine kinase inhibitor, which has been shown to effectively suppress constitutive phosphorylation of the FGF-1 receptor in human ovarian carcinoma cells (1,2,3).
-
Chemical s categoryAromatics, Heterocycles, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors, Pfizer compounds
-
Other nameN-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea; 1-Tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylamino-butylamino)pyrido[2,3-d]pyrimidin-7-yl]urea;
-
Chemical s formulaC26H35Cl2N7O
-
Physical propertiesOff-White Solid
-
Melting temperature229-232°C (dec.)
-
Boiling temperatureNo Data Available
-
Chemical s soluble inChloroform, Methanol
-
Stability conditionsNo Data Available
-
StorageRefrigerator
-
Gene target
-
Gene symbolENPP2, PDCD1, ENPP3, PDCD1LG2, CD274, VSIR
-
Short namePD-161570
-
Alternative namePD-161570
-
Gene info
-
Identity
-
Gene
-
Long gene nameectonucleotide pyrophosphatase/phosphodiesterase 2
-
Synonyms gene
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1995-08-10
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Ectonucleotide pyrophosphatase/phosphodiesterase family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameprogrammed cell death 1
-
Synonyms gene
-
Synonyms gene name
- systemic lupus erythematosus susceptibility 2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1994-05-24
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- V-set domain containing
- CD molecules
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameectonucleotide pyrophosphatase/phosphodiesterase 3
-
Synonyms gene
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1995-08-10
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Ectonucleotide pyrophosphatase/phosphodiesterase family
- CD molecules
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameprogrammed cell death 1 ligand 2
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2003-11-14
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- B7 family
- CD molecules
- Immunoglobulin like domain containing
- Receptor ligands
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameCD274 molecule
-
Synonyms gene
-
Synonyms gene name
- programmed cell death 1 ligand 1
- CD274 antigen
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2003-11-13
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Receptor ligands
- C2-set domain containing
- V-set domain containing
- B7 family
- CD molecules
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameV-set immunoregulatory receptor
-
Synonyms gene
-
Synonyms gene name
- chromosome 10 open reading frame 54
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2005-10-06
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- B7 family
- V-set domain containing
-
VEGA ID