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anti-SEK1/MKK4/JKK1 Antibody

anti-SEK1/MKK4/JKK1 Antibody is available 1 time from Biovision labs

3871-100 | anti-SEK1/MKK4/JKK1 Antibody size: SEK1/MKK4/JKK1 Antibody | 376.04 USD

Catalog number 3871-100
Supplier Biovision
Price 376.04 USD
Size SEK1/MKK4/JKK1 Antibody
1. Gene info
Identity 6844
Gene MAP2K4
Long gene name mitogen-activated protein kinase kinase 4
Synonyms gene
  • SERK1
Synonyms
  • MEK4
  • JNKK1
  • PRKMK4
  • MKK4
GenBank acession
  • L36870
Locus 17p12
Discovery year 1997-11-11
Entrez gene record 6416
Pubmed identfication
  • 7716521
Classification
  • Mitogen-activated protein kinase kinases
  • MicroRNA protein coding host genes
Havana BLAST/BLAT OTTHUMG00000178267
Product images
    #0#.jpeg
Target of this antibody: SEK1/MKK4/JKK1
Alternative names of antibody target: NKK , JNKK1 , MAP kinase kinase 4 , MAP2K4 , MAPK/ERK kinase 4 , MAPKK4 , MEK4 , monkeyK4 , PRKMK4 , SAPK/ERK kinase 1 , SEK1 ,SERK1
Background information: SAPK/Erk kinase (SEK1), also known as MKK4 or Jun kinase kinase (JNKK), activates the MAP kinase homologues SAPK and JNK in response to various cellular stresses and inflammatory cytokines. Activation of SEK1 occurs throμgh phosphorylation of serine and threonine residues at positions 257 and 261, respectively, by MEKK. Like MEK, SEK is a dual-specificity protein kinase that phosphorylates SAPK/JNK at a conserved T*PY* site in its activation loop. Phosphorylation by Akt at Ser80 inhibits SEK1 and suppresses the stress-activated signal transduction.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
This antibody reacts with: Human, mouse, dog
Immunogene sequence: Synthetic peptide surrounding amino acid 347 of mouse SEK1
Concentration of antibody: 0.5 mg/ml
Form of antibody: Liquid
Formulation of this antibody: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification method: Affinity purified
This antibody has been succesfully tested for use in following methods: Western blot
Recommended usage: Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes unphosphorylated and phosphorylated SEK1 from samples of human, mouse, and dog origins.
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetSEK1/MKK4/JKK1
Short name anti-SEK1/MKK4/JKK1 Antibody
Technique Antibody, anti
Alternative name antibody to-SEK1/MKK4/JKK1 (Antibody to)
Alternative technique antibodies
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