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Mouse Monoclonal Anti-UHRF1 Antibody (1H9-D3-E11)

Mouse Monoclonal Anti-UHRF1 Antibody (1H9-D3-E11) is available 1 time from Biovision labs

A1319-100 | Mouse Monoclonal Anti-UHRF1 Antibody (1H9-D3-E11) size: 100 µg | 383.49 USD

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Clonality Monoclonal Antibody (Clone#1H9-D3-E11)
Description Mouse Monoclonal antibody to detect UHRF1
Physical state Colorless liquid
Purity Affinity purified
Raised in Mouse
Gene number 29128
Target UHRF1 (E3 ubiquitin-protein ligase UHRF1, Inverted CCAAT box-binding protein of 90 kDa, Nuclear protein 95, Nuclear zinc finger protein Np95, HuNp95, hNp95, RING finger protein 106, FLJ21925, ICBP90, MGC138707, Np95, RNF106, hNP95)
Package form Affinity purified antibody is supplied in liquid form in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Immunogen Recombinant human UHRF1 protein fragments expressed in E.coli
Protein number Q96T88
Precautions Manifactured in USA. For Research Use Only! Not to be used in humans
Released This antibody is available to order since May 2017
Scientific context Multidomain protein that acts as a key epigenetic regulator by bridging DNA methylation and chromatin modification. Specifically recognizes and binds hemimethylated DNA at replication forks via its YDG domain and recruits DNMT1 methyltransferase to ensure faithful propagation of the DNA methylation patterns through DNA replication. In addition to its role in maintenance of DNA methylation, also plays a key role in chromatin modification: through its tudor-like regions and PHD-type zinc fingers, specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3) and unmethylated at 'Arg-2' (H3R2me0), respectively, and recruits chromatin proteins.
Approved applications with antibody dilution Western blot; 1:1000
Handling and storage Before use gently mix the antibody solution. Store this antibody at -20 °C for 12 months. Refer to the label on vial
Antibody's positive controles Western blot: Mouse heart, 293T, HeLa nuclear extract and HeLa cell lysates
Reacts with Human
Research area Epigenetics
Delivery Shipped to your lab under gel pack
Additional description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
About Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Test Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name Mus musculus
French translation anticorps
Short name Mouse Monoclonal Anti-UHRF1 Antibody (1H9-D3-E11)
Technique Mouse monoclonal, Antibody, Mouse, anti
Host mouse monoclonal
Species Mouse
Alternative name Mouse monoclonal antibody to-UHRF1 (Antibody to) (1H9-D3-E11)
Alternative technique antibodies
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