Rabbit Anti Sheep IL12B Antibody-Biotin

  • Catalog number
    CSB-PA011587LD01SH_100ug
  • Price
    Please ask
  • Size
    100ug
  • Long name
    Rabbit Antibody against Sheep IL12B, Biotin
  • Synonym name
    IL12B Sheep Antibody
  • Species reactivity
    Sheep
  • Tested applications recommended dilutions
    ELISA
  • Conjugation
    Biotin
  • Antibody isotype
    IgG
  • UniProt ID
    P68220
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Purity
    >95%
  • Purification method
    Protein G purified
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant Sheep Interleukin-12 subunit beta protein (23-327AA)
  • Immunogen species
    Sheep
  • Alias
    Cytotoxic lymphocyte maturation factor 40 kDa subunit,IL-12 subunit p40,IL12B
  • Background
    Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC By similarity.Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis By similarity.
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    IL12B Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
  • Additional conjugation
    Biotinylated
  • About
    Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
  • Latin name
    Oryctolagus cuniculus
  • French translation
    anticorps
  • Gene target
    IL12B  
  • Gene symbol
    IL12B
  • Short name
    Anti-IL12B
  • Technique
    Antibody, Rabbit, anti, antibody to, antibodies against human proteins, antibodies for
  • Host
    Rabbit, Rabbits
  • Label
    Biotin
  • Species
    Sheep, The sheep (Ovis aries) ELISAs are detecting sheep proteins and antigens. Some epitopes will also recognize goat proteins. Sheep and goats are also used to produce polyclonals. An adult female sheep is referred to as a ewe a male as a ram, a castrated male as a wether, and a younger sheep as a lamb. Sheeps
  • Alternative name
    IL12B Antibody,Biotin conjugated
  • Alternative technique
    antibodies, rabbit-anti
  • Alternative to gene target
    interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40), CLMF and CLMF2 and IL-12B and IMD28 and IMD29 and NKSF and NKSF2, IL12B and IDBG-55893 and ENSG00000113302 and 3593, protein heterodimerization activity, Extracellular, Il12b and IDBG-164545 and ENSMUSG00000004296 and 16160, IL12B and IDBG-646420 and ENSBTAG00000004741 and 281857
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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