PEDF Antibody

• Catalog number
  6680-30T
• Price
  Please ask
• Size
  30 μg

• Antibody Target
  PEDF
• Target Alternative Name
  Pigment epithelium-derived factor, PEDF, Serpin-F1, SerpinF1, EPC-1, EPC1, PIG35
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Human recombinant PEDF, Cat # 4988
• Accession
  P36955
• Gene Id
  5176
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  30 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
• Purification
  Affinity Purified Antibody
• Application
  Western blot
• Positive Control
  Western Blot: Jurkat cell lysate, 3T3 cell lysate, mouse muscle lysate, rat kidney lysate, recombinant protein
• Application And Usages
  Western blot: 1-4 µg
• Description
  PEDF is a non-inhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties. PEDF is a 50 kDa glycoprotein created and secreted in many tissues all the way through the body. A key component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells. Additionally, PEDF is capable to inhibit the activity of angiogenic factors such as VEGF and FGF-2. The recognition of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin. The unique range of PEDF activities associate it as a potential therapeutic agent for the treatment of vasculature related neurodegenerative diseases such as age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR).
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PEDF  
• Gene symbol
  SERPINF1
• Short name
  PEDF Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  PEDF (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8824
• Gene
  SERPINF1
• Long gene name
  serpin family F member 1
• Synonyms gene
  • PEDF
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
  • pigment epithelium-derived factor
• Synonyms
  • EPC-1
  • PIG35
• Synonyms name
  • alpha-2 antiplasmin
  • proliferation-inducing protein 35
• GenBank acession
  • M76979
• Locus
  17p13.3
• Discovery year
  1993-05-18
• Entrez gene record
  5176
• Pubmed identfication
  • 8434014
  • 24172014
• RefSeq identity
  • NM_002615
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000090571
• Locus Specific Databases
  • SERPINF1 variant database

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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