Brefeldin A

• Catalog number
  B677240
• Price
  Please ask
• Size
  5 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  In Stock
• Cas number
  20350-15-6
• Chemical s molecular weight
  280.36
• Chemical s main applications
  A macrolide isolated from Penicillium brefeldianum. It affects the vesticular transport of the Golgi apparatus and induces DNA fragmentation which leads to apoptosis.
• Chemical s category
  Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
• Other name
  γ-4-Dihdyroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic Acid, ∂-Lactone, BFA, Cyanein, Ascotoxin, Decumbin; NSC 244390; NSC 56310; NSC 89671; Nectrolide; Synergisidin;
• Chemical s formula
  C16H24O4
• Physical properties
  White Solid
• Melting temperature
  206-208˚C
• Boiling temperature
  No Data Available
• Chemical s soluble in
  Methanol (Slightly)
• Stability conditions
  No Data Available
• Storage
  -20°C Freezer
• Chemical s specifications

• Gene target
  Brefeldin  
• Gene symbol
  GBF1, CTBP1, ARFGEF2
• Short name
  Brefeldin A
• Alternative name
  Brefeldin A

Gene info

• Identity
  HGNC:4181
• Gene
  GBF1
• Long gene name
  golgi brefeldin A resistant guanine nucleotide exchange factor 1
• Synonyms gene name
  • golgi-specific brefeldin A resistance factor 1
• Synonyms
  • KIAA0248
  • ARF1GEF
• GenBank acession
  • D87435
• Locus
  10q24.32
• Discovery year
  1999-01-14
• Entrez gene record
  8729
• Pubmed identfication
  • 9828135
• Classification
  • Sec7 family
• VEGA ID
  OTTHUMG00000018955

Gene info

• Identity
  HGNC:2494
• Gene
  CTBP1
• Long gene name
  C-terminal binding protein 1
• Synonyms
  • BARS
• Synonyms name
  • brefeldin A-ribosylated substrate
• GenBank acession
  • U37408
• Locus
  4p16.3
• Discovery year
  1997-08-22
• Entrez gene record
  1487
• Pubmed identfication
  • 9479502
• RefSeq identity
  • NM_001328
• VEGA ID
  OTTHUMG00000089259

Gene info

• Identity
  HGNC:15853
• Gene
  ARFGEF2
• Long gene name
  ADP ribosylation factor guanine nucleotide exchange factor 2
• Synonyms gene name
  • ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
• Synonyms
  • BIG2
• Synonyms name
  • Brefeldin A-inhibited guanine nucleotide-exchange protein 2
• GenBank acession
  • AF084521
• Locus
  20q13.13
• Discovery year
  2001-06-21
• Entrez gene record
  10564
• Pubmed identfication
  • 10212200
• RefSeq identity
  • NM_006420
• Classification
  • ARFGEF family
  • A-kinase anchoring proteins
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000032687

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