Recombinant TNF Receptor Associated Factor 6 (TRAF6)

  • Catalog number
    RPG751Hu01
  • Price
    Please ask
  • Size
    800
  • Source
    Prokaryotic expression
  • Predicted Molecular Mass KD
    35.2kDa
  • Accurate Molecular Mass KD
    NA
  • Organism species
    Homo sapiens (Human)
  • Item Name
    TNF Receptor Associated Factor 6
  • Alternative Names
    RNF85; E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer
  • Research Area
    Tumor immunity;
  • Buffer Formulation
    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits
    Freeze-dried powder
  • Purity
    ≥ 95%
  • Protein length
    Ala153~Pro423
  • Tag
    two N-terminal Tags, His-tag and T7-tag
  • Expression System
    Prokaryotic expression
  • Application
    Positive Control; Immunogen; SDS-PAGE; WB.
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene
    Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
  • Gene target
  • Gene symbol
    TNF, TRAF6, TNFRSF1A, TNFRSF1B, LTBR
  • Short name
    Recombinant TNF Receptor Associated Factor 6 (TRAF6)
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Host
    E.coli
  • Species
    Homo sapiens (Human)
  • Alternative name
    Rec. tumor necrosis factor Receptor Associated Factor 6 (tumor necrosis factor receptor-associated factor 6, E3 ubiquitin protein ligase)
  • Alternative technique
    rec
  • Alternative to gene target
    TNF receptor-associated factor 6, E3 ubiquitin protein ligase, MGC:3310 and RNF85, TRAF6 and IDBG-40102 and ENSG00000175104 and 7189, protein N-terminus binding, nuclei, Traf6 and IDBG-193222 and ENSMUSG00000027164 and 22034, TRAF6 and IDBG-636763 and ENSBTAG00000036009 and 539124
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    TNF receptor associated factor 6
  • Synonyms gene name
    • TNF receptor-associated factor 6, E3 ubiquitin protein ligase
  • Synonyms
  • Locus
  • Discovery year
    1997-06-12
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Ring finger proteins
    • TNF receptor associated factors
  • VEGA ID
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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