Mouse anti p15 - ink4b

• Catalog number
  C110M
• Price
  Please ask
• Size
  100 μg

• Category
  Primary Antibodies
• Long description
  The immunogen for the anti-human p15 was a his-tagged recombinant full length p15 protein recognizing a 15kDa protein. The p15ink4b tumor suppressor protein shows no cross reactivity with the closely related inhibitors including p16ink4a and p19ink4d. p15ink4b is a specific inhibitor of cdk4/cdk6, and is periodically expressed during cell cycle.
• Antibody come from
  A his-tagged recombinant full length p15 protein recognizing a 15kDa protein
• Other description
  Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
• Clone
  DCS114.1
• Antigen antibody binding interaction
  Mouse anti p15 - ink4b Antibody
• Antibody is raised in
  Mouse
• Antibody s reacts with
  Human
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Western Blot, Immunoprecipitation, Immunohistochemistry (paraffin)
• Antibody s suited for
  Applications: 1-5 ug /ml for Western Blot, Immunohistochemistry, Immunoprecipitation (co-precipitates cdk4/cdk6)
• Storage
  -20ºC
• Relevant references
  1) C. Sherr, et.al. (1995) Gene & Dev..9, 1149-1163 _x000B__x000B_2) Sakellariou, S., et al. 'Immunohistochemical Expression of P15 (INK4B) and SMAD4 in Advanced Gastric Cancer.' Anticancer Research (2008), 28, 1079-1083
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  p15   ink4b  
• Gene symbol
  CDKN2B
• Short name
  Mouse anti p15 - ink4b
• Technique
  Mouse, anti, antibody to, mouses
• Host
  mouse
• Isotype
  IgG1
• Label
  unlabeled
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to p15 - ink4b
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:1788
• Gene
  CDKN2B
• Long gene name
  cyclin dependent kinase inhibitor 2B
• Synonyms gene name
  • cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
• Synonyms
  • P15
  • MTS2
  • INK4B
  • TP15
  • CDK4I
  • p15INK4b
• GenBank acession
  • AB060808
• Locus
  9p21.3
• Discovery year
  1995-06-14
• Entrez gene record
  1030
• Pubmed identfication
  • 8078588
• RefSeq identity
  • NM_004936
• VEGA ID
  OTTHUMG00000019691

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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