anti-HDAC4 (phospho Ser632) Antibody
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Catalog number
79-468
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Price
Please ask
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Size
0.1 mg
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Gene info
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
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Gene names
HD4, AHO3, BDMR, HDACA, HA6116, HDAC-4, HDAC-A, AML1, CBFA2, HD4
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Antibodie s label
unlabelled serum
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Purity
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
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Ab raised in
Rabbit
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Type
Polyclonal
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Spicific to
This antibody detects endogenous level of HDAC4 only when phosphorylated at serine 632.
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Antigen
HDAC4 (Phospho-Ser632) antibody was made against a peptide sequence around phosphorylation site of serine 632 (A-Q-S (p) -S-P) derived from Human HDAC4.
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Immuno application
Western Blot
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Antibody advice
Western Blot: 1:500~1:1000
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Suspention pH azide
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Keep at
Store antibody at -20 grades C for up to one year.
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Works with
Human, Mouse, Rat
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Omim nr
153085395
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Ncbi nr
NP_006028.2
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KDa
140 kDa
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
9759
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GENE symbol
HDAC4
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Antigene name
histone deacetylase 4
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Source
Homo sapiens
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Protein nr
P56524
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
HDAC4-AS1, HDAC4
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Short name
anti-HDAC4 (phospho Ser632) Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toHDAC4 (phosphorilated Ser632) (antibody to-)
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Alternative technique
antibodies
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Alternative to gene target
histone deacetylase 4, AHO3 and BDMR and HA6116 and HD4 and HDAC-4 and HDAC-A and HDACA, HDAC4 and IDBG-84594 and ENSG00000068024 and 9759, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, Hdac4 and IDBG-181579 and ENSMUSG00000026313 and 208727, HDAC4 and IDBG-642244 and ENSBTAG00000017764 and 517559
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Gene info
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Identity
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Gene
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Long gene name
HDAC4 antisense RNA 1
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Locus
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Discovery year
2018-09-27
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Entrez gene record
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RefSeq identity
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Classification
Gene info
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Identity
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Gene
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Long gene name
histone deacetylase 4
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Synonyms gene
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Synonyms gene name
- brachydactyly-mental retardation syndrome
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Synonyms
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GenBank acession
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Locus
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Discovery year
2000-11-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Histone deacetylases, class IIA
- MicroRNA protein coding host genes
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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