Verapamil HCl, L-type Ca channel blocker

  • Catalog number
    SIH-308-5G
  • Price
    Please ask
  • Size
    5 g
  • Stock availabilitIn Stock
    In Stock
  • CAS number
    152-11-4
  • Description
    L-type Ca channel blocker
  • Molecular weight
    491,07 g/mol
  • Primary research fields
    Neuroscience, Ion Channels, Calcium Channels, Voltage-Gated Calcium Channels
  • Other name
    2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile hydrochloride (1:1)
  • Product category
    Small Molecules
  • Product type
    Inhibitor
  • Chemical formula
    C27H38N2O4•HCl
  • Origin
    Synthetic
  • Purity pourcentage
    >98%
  • Soluble in
    Soluble to 100 mM in ethanol and to 50 mM in water
  • Physical appearance
    White Solid
  • Storage recommendations
    -20ºC
  • Shipping recommendations
    Shipped Ambient
  • Safety information
    Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R23/24/25 - Toxic by inhilation, in contact with skin and if swallowed R60 - May impair fertility R61 - May cause harm to the unborn child R68 - Possible risk of irreversible effects Hazard Phrases: H301-H311-H331 Precautionary Phrases: P261-P280-P301 + P310-P311
  • PubChem number
    62969
  • Scientific context
    Verapamil is an L-type calcium channel blocker of the phenylalkylamine class. It has been used in the treatment of hypertension, angina pectoris, cardiac arrhythmia, and cluster headaches. Its mechanism is to block voltage-dependent calcium channels (1).
  • Bibliography
    1. Livesley B., and Oram S. (1972) Br Med J. 2(5804): 50.
  • Release date
    8-Apr-2011
  • PubMed number
    Refer to PubMed
  • Tested applications
    To be tested
  • Tested reactivity
    To be tested
  • Representative figure legend
    Chemical structure of Verapamil HCl (SIH-308), a L-type Ca channel blocker. CAS #: 152-11-4. Molecular Formula: C27H38N2O4.HCl. Molecular Weight: 491.07 g/mol. Chemical structure of Verapamil HCl, a L-type Ca channel blocker (SIH-308). CAS # 152-11-4. Molecular Formula: C27H38N2O4.HCl.
  • Warning information
    Non-hazardous
  • Country of production
    Canada
  • Total weight kg
    0.25
  • Net weight g
    5
  • Gene target
  • Short name
    Verapamil HCl, L- Ca channel blocker
  • Alternative name
    Verapamil HCl, L-classification Ca channel blocker
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