Conduritol B Epoxide

  • Catalog number
    9574-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    D,L-1,2-Anhydro-myo-inositol; CBE
  • Description
    Conduritol B epoxide (CBE) is an irreversible inhibitor of glucocerebrosidase, also known as acid β-glucosidase, glucosylceramidase, GBA, or GBA1 (IC₅₀ = 9 μM). Inhibition of this lysosomal glucosidase results in the accumulation of glucocerebroside without affecting cell viability, lysosomal enzyme release, or the activity of intracellular enzymes. It also does not inhibit non-lysosomal glucosylceramidase or cytosolic β-glucosidase.
  • CAS Number
    6090-95-5
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₆H₁₀O₅
  • Molecular Weight
    162.14
  • Cell Permeable
    Yes
  • Purity
    ≥98%
  • Solubilities
    DMSO ~25 mg/ml)
  • Handling
    Protect from air and moisture
  • Tag Line
    An irreversible inhibitor of glucocerebrosidase
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00077326
  • PubChem CID
    119054
  • SMILES
    C1(C(C(C2C(C1O)O2)O)O)O
  • InChi
    InChI=1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H/t1-,2-,3+,4+,5-,6+/m0/s1
  • InChi Key
    ZHMWOVGZCINIHW-FTYOSCRSSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Conduritol B Epoxide
  • Alternative name
    Conduritol B Epoxide
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