Conduritol B Epoxide
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Catalog number9574-25
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PricePlease ask
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Size25 mg
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Alternative_nameD,L-1,2-Anhydro-myo-inositol; CBE
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DescriptionConduritol B epoxide (CBE) is an irreversible inhibitor of glucocerebrosidase, also known as acid β-glucosidase, glucosylceramidase, GBA, or GBA1 (IC₅₀ = 9 μM). Inhibition of this lysosomal glucosidase results in the accumulation of glucocerebroside without affecting cell viability, lysosomal enzyme release, or the activity of intracellular enzymes. It also does not inhibit non-lysosomal glucosylceramidase or cytosolic β-glucosidase.
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CAS Number6090-95-5
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₆H₁₀O₅
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Molecular Weight162.14
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Cell PermeableYes
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Purity≥98%
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SolubilitiesDMSO ~25 mg/ml)
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HandlingProtect from air and moisture
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Tag LineAn irreversible inhibitor of glucocerebrosidase
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD00077326
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PubChem CID119054
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SMILESC1(C(C(C2C(C1O)O2)O)O)O
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InChiInChI=1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H/t1-,2-,3+,4+,5-,6+/m0/s1
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InChi KeyZHMWOVGZCINIHW-FTYOSCRSSA-N
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MSDS AvailableYes
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Gene target
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Short nameConduritol B Epoxide
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Alternative nameConduritol B Epoxide
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