Mouse anti p107

• Catalog number
  N100M
• Price
  Please ask
• Size
  100 μg

• Category
  Primary Antibodies
• Long description
  The immunogen used was a recombinant protein to the N terminus of p107. p107 is related both in structure and function to the retinoblastoma tumor suppressor protein and p130 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p107 converts E2F transcription factors from transcriptional activators to transcriptional repressors. KAB6 recognizes both the phosphorylated and unphosphorylated forms of p107 at a MW of 107kDa.
• Antibody come from
  Recombinant GST protein to the N terminus of p107
• Other description
  Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
• Clone
  KAB6
• Antigen antibody binding interaction
  Mouse anti p107 Antibody
• Antibody is raised in
  Mouse
• Antibody s reacts with
  Human, Mouse, Rat
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Western Blot
• Antibody s suited for
  Applications: Western Blots at 1:1000
• Storage
  -20ºC
• Relevant references
  no information yet
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  p107  
• Gene symbol
  RBL1, E2F4
• Short name
  Mouse anti p107
• Technique
  Mouse, anti, antibody to, mouses
• Host
  mouse
• Isotype
  IgG1
• Label
  unlabeled
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to p107
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:9893
• Gene
  RBL1
• Long gene name
  RB transcriptional corepressor like 1
• Synonyms gene name
  • retinoblastoma-like 1
• Synonyms
  • p107
  • cp107
  • PRB1
• GenBank acession
  • L14812
• Locus
  20q11.23
• Discovery year
  1994-01-07
• Entrez gene record
  5933
• Pubmed identfication
  • 1833063
• RefSeq identity
  • NM_002895
• VEGA ID
  OTTHUMG00000032406

Gene info

• Identity
  HGNC:3118
• Gene
  E2F4
• Long gene name
  E2F transcription factor 4
• Synonyms gene name
  • E2F transcription factor 4, p107/p130-binding
• Synonyms
  • E2F-4
• GenBank acession
  • BC021050
• Locus
  16q22.1
• Discovery year
  1995-02-01
• Entrez gene record
  1874
• Pubmed identfication
  • 7958924
  • 7892279
• RefSeq identity
  • NM_001950
• Classification
  • E2F transcription factors
• VEGA ID
  OTTHUMG00000172975

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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