TLR5(Toll-like receptor 5) Polyclonal Antibody

  • Catalog number
    3555-100
  • Price
    Please ask
  • Size
    100 µg
  • Antibody Target
    TLR5(Toll-like receptor 5)
  • Target Alternative Name
    Toll Like Receptor 5
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human, Mouse, Rat
  • Immunogen Sequence
    Synthetic peptide surrounding amino acid 330 of human TLR5
  • Accession
    O60602
  • Gene Id
    7100
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    0.5 mg/ml
  • Formulation
    100 ml protein A purified rabbit anti-TLR5 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 10% glycerol and 0.02% thimerosal.
  • Purification
    Affinity purified rabbit IgG
  • Application
    Western blot
  • Application And Usages
    Western blot: 1-4 µg
  • Description
    The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology(TH) domain,which is essential for Toll-induced signal transduction.TLR1,as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride(LPS) stimulation, which results in the activation and translocation of NFkB and suggests that these receptors are involved in mediating inflammatory responses. TLR6 is highly homologous to TLR1, and like other members of TLR family, it induces NFkB Signaling upon activation. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes.
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Dot Blot Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Group
    Polyclonals and antibodies
  • About
    Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
  • Additional description
    The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    TLR5
  • Short name
    TLR5(Toll-like receptor 5) Polyclonal Antibody
  • Technique
    Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
  • Isotype
    rabbit IgG
  • Alternative name
    toll-like receptor 5(Toll-like receptor 5) polyclonal (antibody to-)
  • Alternative technique
    polyclonals, antibodies
  • Alternative to gene target
    toll-like receptor 5, MELIOS and SLE1 and SLEB1 and TIL3, TLR5 and IDBG-106840 and ENSG00000187554 and 7100, protein binding, Plasma membranes, Tlr5 and IDBG-259066 and ENSMUSG00000079164 and 53791, TLR5 and IDBG-648348 and ENSBTAG00000000477 and 444870
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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