XRCC6 Antibody

• Catalog number
  F49015-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  XRCC6
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, FACS, IF, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
• Notes
  Titration of the XRCC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This XRCC6 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P12956
• Purity
  Antigen affinity
• Description
  XRCC6 is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
• Immunogen
  A portion of amino acids 521-548 from the human protein was used as the immunogen for this XRCC6 antibody.
• Storage
  Aliquot the XRCC6 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  XRCC6  
• Gene symbol
  XRCC6
• Short name
  Anti-XRCC6
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to XRCC6
• Alternative technique
  antibodies
• Alternative to gene target
  X-ray repair complementing defective repair in Chinese hamster cells 6, CTC75 and CTCBF and G22P1 and KU70 and ML8 and TLAA, XRCC6 and IDBG-9323 and ENSG00000196419 and 2547, 5'-deoxyribose-5-phosphate lyase activity, nuclei, Xrcc6 and IDBG-165874 and ENSMUSG00000022471 and 14375, XRCC6 and IDBG-641933 and ENSBTAG00000006103 and 510132

Gene info

• Identity
  HGNC:4055
• Gene
  XRCC6
• Long gene name
  X-ray repair cross complementing 6
• Synonyms gene
  • G22P1
• Synonyms gene name
  • thyroid autoantigen 70kD (Ku antigen)
  • thyroid autoantigen 70kDa (Ku antigen)
  • X-ray repair complementing defective repair in Chinese hamster cells 6
• Synonyms
  • D22S731
  • D22S671
  • KU70
  • ML8
• Synonyms name
  • Ku autoantigen, 70kDa
• GenBank acession
  • J04607
• Locus
  22q13.2
• Discovery year
  1988-05-11
• Entrez gene record
  2547
• Pubmed identfication
  • 9200330
  • 9223317
• RefSeq identity
  • NM_001469
• Classification
  • DNA helicases
• VEGA ID
  OTTHUMG00000151190

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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