Perifosine (KRX-0401)
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Catalog number1592-5
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PricePlease ask
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Size5 mg
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Alternative_nameKRX-0402
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DescriptionBelongs to an alkylphospholipid class of antineoplastic compounds that display potent antiproliferative activity in several in vitro and in vivo human tumor models. Perifosine induces apoptotic cell death in a variety of tumor cell lines. Apoptosis is induced in a time- and dose-dependent manner in U937 and Jurkat T human leukemia cell lines but not in normal vascular endothelial cells.
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CAS Number157716-52-4
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₅H₅₃NO₄P
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Molecular Weight462.66
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Cell PermeableYes
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Purity≥99%
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SolubilitiesH₂O (10 mg/ml)
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HandlingProtect from light and moisture
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Tag LineAn antineoplastic agent
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24months
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MDL NumberMFCD00927554
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PubChem CID148178
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SMILESCCCCCCCCCCCCCCCCCCOP(=O)(O)OC1CC[N+](CC1)(C)C
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InChiInChI=1S/C25H52NO4P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29- 31(27,28)30-25-20-22-26(2,3)23-21-25/h25H,4-24H2,1-3H3/p+1
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InChi KeySZFPYBIJACMNJV-UHFFFAOYSA-O
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MSDS AvailableYes
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Gene target
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Short namePerifosine (KRX-0401)
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Alternative namePerifosine (KRX-0401)
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