Perifosine (KRX-0401)

  • Catalog number
    1592-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    KRX-0402
  • Description
    Belongs to an alkylphospholipid class of antineoplastic compounds that display potent antiproliferative activity in several in vitro and in vivo human tumor models. Perifosine induces apoptotic cell death in a variety of tumor cell lines. Apoptosis is induced in a time- and dose-dependent manner in U937 and Jurkat T human leukemia cell lines but not in normal vascular endothelial cells.
  • CAS Number
    157716-52-4
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₅H₅₃NO₄P
  • Molecular Weight
    462.66
  • Cell Permeable
    Yes
  • Purity
    ≥99%
  • Solubilities
    H₂O (10 mg/ml)
  • Handling
    Protect from light and moisture
  • Tag Line
    An antineoplastic agent
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24months
  • MDL Number
    MFCD00927554
  • PubChem CID
    148178
  • SMILES
    CCCCCCCCCCCCCCCCCCOP(=O)(O)OC1CC[N+](CC1)(C)C
  • InChi
    InChI=1S/C25H52NO4P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29- 31(27,28)30-25-20-22-26(2,3)23-21-25/h25H,4-24H2,1-3H3/p+1
  • InChi Key
    SZFPYBIJACMNJV-UHFFFAOYSA-O
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Perifosine (KRX-0401)
  • Alternative name
    Perifosine (KRX-0401)
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